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HIV/AIDS Therapy

Research from Seoul National University, Research Institute of Pharmaceutical Sciences in the area of HIV/AIDS therapy published

Published in AIDS Weekly, April 26th, 2010

New investigation results, 'Lignan, sesquilignans and dilignans, novel HIV-1 protease and cytopathic effect inhibitors purified from the rhizomes of Saururus chinensis,' are detailed in a study published in Antiviral Research. According to a study from Seoul, Korea, "Five lignans were isolated from the ethyl acetate extracts of Saururus chinensis rhizomes and evaluated for anti-HIV-1 activity. Their structures were elucidated as two dilignans, manassantin A (1), manassantin B (2), two sesquilignans, saucerneol B (3) and saucerneol C (4), and a new lignan, saururin B (5) by spectroscopic analysis."

"Of these components, manassantin A (1) and saururin B (5) showed...

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