Research
Researchers identify the source of 'noise' in HIV
Published in AIDS Weekly, May 3rd, 2010
New research identifies a molecular mechanism that the human immunodeficiency virus (HIV) appears to utilize for generating random fluctuations called "noise" in its gene expression. The study, published by Cell Press in the April 20th issue of the Biophysical Journal, pinpoints the likely source of HIV gene-expression noise and provides intriguing insight into the role of this noise in driving HIV's fate decision between active replication and latency.
After infecting a human cell, HIV integrates into the genome and typically begins to actively replicate. However, the virus can also enter a long-lived latent state, which remains the greatest barrier to eradicating...
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Source: AIDS Weekly (2010-05-03)
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