HIV/AIDS Immunology
Research from A. Berger et al has provided new information about HIV/AIDS immunology
Published in AIDS Weekly, May 3rd, 2010
A new study, 'Interaction of Vpx and apolipoprotein B mRNA-editing catalytic polypeptide 3 family member A (APOBEC3A) correlates with efficient lentivirus infection of monocytes,' is now available. "The accessory protein Vpx is encoded by lentiviruses of the human immunodeficiency virus type 2 (HIV-2) and the simian immunodeficiency SIVsm/SIVmac lineage. It is packaged into virions and is indispensable in early steps of monocyte infection," researchers in Langen, Germany report.
"HIV-1, which does not encode Vpx, is not able to infect human monocytes, but Vpx enables infection with HIV-1. The underlying mechanism is not completely understood. In this work, we focus on...
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Source: AIDS Weekly (2010-05-03)
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