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HIV/AIDS

Research findings from University of Georgia update understanding of HIV/AIDS

Published in AIDS Weekly, May 3rd, 2010

"It has been suggested that superinfection of HIV positive individuals with heterologous HIV strains could lead to faster progression to AIDS, generating concern over the risks of exposure to new infections in those already infected. A mathematical model of the within-host dynamics of two sequential infections with strains of HIV describing activation and infection of immune cells was developed," scientists in the United States report.

"Multiple stochastic realisations describing progression to AIDS in the individual were generated, comparing the situation with and without superinfection. It was found that the susceptibility of immune cells to dual infection is crucial...

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