Mononuclear Phagocyte System
Researchers at Universite Laval target mononuclear phagocyte system
Published in AIDS Weekly, May 10th, 2010
Researchers detail in 'Malaria hemozoin modulates susceptibility of immature monocyte-derived dendritic cells to HIV-1 infection by inducing a mature-like phenotype,' new data in mononuclear phagocyte system. "Together, Plasmodium falciparum (P. falciparum) and HIV-1 infections cause more than four million deaths a year. There is still limited information about the putative impact of the malaria pigment hemozoin (HZ) on the dissemination of HIV-1," scientists in Quebec, Canada report.
"As so, we propose a premise where HZ present in human dendritic cells (DCs) could modulate HIV-1 transfer to CD4(+) T cells. We report here that HZ promotes transmission of...
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Source: AIDS Weekly (2010-05-10)
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