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Simian Immunodeficiency Virus

New findings from M. Stone and co-researchers in the area of simian immunodeficiency virus described

Published in AIDS Weekly, July 12th, 2010

Research findings, 'A limited number of simian immunodeficiency virus (SIV) env variants are transmitted to rhesus macaques vaginally inoculated with SIVmac251,' are discussed in a new report. "Single-genome amplification (SGA) and sequencing of HIV-1 RNA in plasma of acutely infected humans allows the identification and enumeration of transmitted/founder viruses responsible for productive systemic infection. Use of this strategy as a means for identifying transmitted viruses suggested that intrarectal simian immunodeficiency virus (SIV) inoculation of macaques recapitulates key features of human rectal infection," investigators in the United States report.

"However, no...

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