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HIV/AIDS

Research conducted at National Institute of Diabetes and Digestive and Kidney Disease has provided new information about HIV/AIDS

Published in AIDS Weekly, July 12th, 2010

New research, 'Mutremdamide A and koshikamides C-H, peptide inhibitors of HIV-1 entry from different Theonella species,' is the subject of a report. According to a study from the United States, "A new sulfated cyclic depsipeptide, termed mutremdamide A, and six new highly N-methylated peptides, termed koshikamides C-H, were isolated from different deep-water specimens of Theonella swinhoei and Theonella cupola. Their structures were determined using extensive 2D NMR, ESI, or CDESI and QTOF-MS/MS experiments and absolute configurations established by quantum mechanical calculations, advanced Marfey's method, and chiral HPLC."

"Mutremdamide A displays a rare...

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