HIV/AIDS
Scientists at Institute of Organic Chemistry and Biochemistry detail research in HIV/AIDS
Published in AIDS Weekly, August 16th, 2010
Data detailed in 'Effect of dimerizing domains and basic residues on in vitro and in vivo assembly of Mason-Pfizer monkey virus and human immunodeficiency virus' have been presented. According to a study from Prague, Czech Republic, "Assembly of immature retroviral particles is a complex process involving interactions of several specific domains of the Gag polyprotein localized mainly within capsid protein (CA), spacer peptide (SP), and nucleocapsid protein (NC). In the present work we focus on the contribution of NC to the oligomerization of CA leading to assembly of Mason-Pfizer monkey virus (M-PMV) and HIV-1."
"Analyzing in vitro assembly of substitution and deletion...
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Source: AIDS Weekly (2010-08-16)
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