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HIV/AIDS

Findings in HIV/AIDS reported from M. Tagliamonte and co-researchers

Published in AIDS Weekly, October 11th, 2010

Researchers detail in 'Constitutive expression of HIV-VLPs in stably transfected insect cell line for efficient delivery system,' new data in HIV/AIDS. "We have previously developed HIV-1 Pr55gag-based virus-like particles (HIV-VLPs) as presentation and delivery model using a transient Baculovirus expression system. Here we describe the establishment and characterization of stably transfected insect cell line for the constitutive and reproducible production of HIV-VLPs," researchers in Naples, Italy report.

"The persistence of HIV gag coding gene has been verified in clonal resistant insect cells and the protein expression has been confirmed by Western blot analysis....

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