HIV/AIDS

Findings in HIV/AIDS reported from INSERM

Published in AIDS Weekly, January 10th, 2011

2011 JAN 10 -- In this recently published article, scientists in Paris, France conducted a study "To determine whether and how protease inhibitors (PIs) could affect vascular aging. HIV therapy with PIs is associated with an increased risk of premature cardiovascular disease."

"The effect of ritonavir and a combination of lopinavir and ritonavir (for 30 days) on senescence, oxidative stress, and inflammation was evaluated in human coronary artery endothelial cells (HCAECs). These HCAECs were either cotreated or not cotreated with pravastatin or farnesyl transferase inhibitor (FTI)-277 or with 2 antioxidants (manganese [III] tetrakis [4-benzoic acid]...

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Source: AIDS Weekly (2011-01-10)

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