HIV/AIDS and Kaposi Sarcoma
Investigators at Case Western Reserve University, Ireland Cancer Center zero in on HIV/AIDS and Kaposi sarcoma
Published in AIDS Weekly, January 10th, 2011
2011 JAN 10 -- Research findings, 'Phase II AIDS malignancy consortium trial of topical halofuginone in AIDS-related Kaposi sarcoma,' are discussed in a new report. "Using a novel blinded intrapatient vehicle control design, we conducted a phase II study of topically administered halofuginone, an angiogenesis inhibitor that inhibits collagen type-I and matrix metalloproteinases (MMPs), in patients with AIDS-related Kaposi sarcoma. Serial Kaposi sarcoma biopsies assessed treatment effects on angiogenic factors and Kaposi sarcoma herpesvirus-latency associated nuclear antigen-1 (KSHV-LANA)," researchers in the United States report.
"We observed marked...
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Source: AIDS Weekly (2011-01-10)
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