HIV/AIDS

New HIV/AIDS Findings from S. Nukuzuma and Co-Authors Described

Published in AIDS Weekly, January 17th, 2011

2011 JAN 17 -- According to a study from Kobe, Japan, "The high incidence of progressive multifocal leukoencephalopathy (PML) in AIDS patients compared with many other immunosuppressive diseases suggests that HIV-1 infection is strictly related to the activation of JC virus (JCV) propagation."

"In this report, propagation of PML-type JCV in COS-7-derived cell lines stably expressing HIV-1 Tat (COS-tat cells) has been examined. In COS-tat cells, production of viral particles and replication of genomic DNA were markedly increased compared to COS-7 cells, as judged by HA and real-time PCR analyses," wrote S. Nukuzuma and colleagues.

The...

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Source: AIDS Weekly (2011-01-17)

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