HIV/AIDS
Data from National Institutes of Health Advance Knowledge in HIV/AIDS
Published in AIDS Weekly, February 21st, 2011
2011 FEB 21 -- "Administration of recombinant human interleukin (IL)-7 leads to CD4 and CD8 T-cell expansions in HIV-infected individuals, demonstrating promising capacity for immune reconstitution. However, a proportion of patients treated with recombinant human IL-7 experience transient increases in plasma HIV-RNA ('blips'), possibly reflecting 'purging' of a quiescent reservoir that provides a barrier to viral eradication," scientists writing in the journal AIDS report.
"To identify the sources of HIV detected during transient viremic episodes following IL-7 administration, viral quasispecies were analyzed in a total of 281 primary sequences...
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Source: AIDS Weekly (2011-02-21)
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