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Investigators at St. Jude Children's Research Hospital Release New Data on Clinical Trials Research

Published in AIDS Weekly, May 23rd, 2011

2011 MAY 23 -- According to a study from Memphis, United States, "HIV-infected youth are at risk of hepatitis B infection and should be vaccinated. Previous reports suggest reduced response to standard hepatitis B vaccine regimens."

"HIV-infected youth, aged 12 to younger than 25 years, were randomly assigned to one of three treatment arms: Arm 1: Engerix B, 20 mg HBsAg; Arm 2: Engerix B (GlaxoSmithKline, Rixensart, Belgium), 40 mg; and Arm 3: Twinrix (GlaxoSmithKline, Rixensart, Belgium), 20 mg HBsAg combined with 720 ELU hepatitis A antigen. Vaccines were administered at Weeks 0, 4, and 24. Characteristics of evaluable patients (n = 336) at entry were...

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