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New HIV/AIDS Research from Catholic University Discussed

Published in AIDS Weekly, January 16th, 2012

2012 JAN 16 -- In this recent report published in the journal Virology, researchers in Louvain, Belgium conducted a study "To trace the evolutionary patterns underlying evolution of coreceptor use within a host, we studied an HIV-1 transmission pair involving a donor who exclusively harbored CCR5-using (R5) variants throughout his entire disease course and a recipient who developed CXCR4-using variants. Over time, R5 variants in the donor optimized coreceptor use, which was associated with an increased number of potential N-linked glycosylation sites (PNGS) and elevated V3 charge in the viral envelope."

"Interestingly, R5 variants that were...

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