HIV/AIDS
Researchers' Work from Imperial College London Focuses on HIV/AIDS
Published in AIDS Weekly, March 5th, 2012
2012 MAR 5 -- New research, "MMP-1 drives immunopathology in human tuberculosis and transgenic mice," is the subject of a report. According to the authors of a study from London, United Kingdom, "Mycobacterium tuberculosis can cause lung tissue damage to spread, but the mechanisms driving this immunopathology are poorly understood. The breakdown of lung matrix involves MMPs, which have a unique ability to degrade fibrillar collagens at neutral pH."
"To determine whether MMPs play a role in the immunopathology of tuberculosis (TB), we profiled MMPs and their inhibitors, the tissue inhibitor of metalloproteinases (TIMPs), in sputum and bronchoalveolar...
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Source: AIDS Weekly (2012-03-05)
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