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HIV/AIDS

Findings in HIV/AIDS Reported from Harvard School of Medicine

Published in AIDS Weekly, March 5th, 2012

2012 MAR 5 -- Research findings, "Inhibition of HIV transmission in human cervicovaginal explants and humanized mice using CD4 aptamer-siRNA chimeras," are discussed in a new report. According to the authors of recent research published in the The Journal of Clinical Investigation, "The continued spread of the HIV epidemic underscores the need to interrupt transmission. One attractive strategy is a topical vaginal microbicide."

"Sexual transmission of herpes simplex virus type 2 (HSV-2) in mice can be inhibited by intravaginal siRNA application. To overcome the challenges of knocking down gene expression in immune cells susceptible to HIV infection,...

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