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Cyclacel Group, plc
Company announces discovery of Aurora kinase inhibitors
January 9th, 2005
Cyclacel Group, plc, a U.K.-based biopharmaceutical company, announced the discovery of a novel series of small-molecule, cell-cycle drugs inhibiting Aurora kinase in a poster presentation at the American Association for Cancer Research Cell Cycle and Cancer: Pathways and Therapies conference. Cyclacel has advanced a lead compound from this series into preclinical development and is studying several fast-follower candidates. Aurora kinases are enzymes that help dividing cells share their materials among two daughter cells. In many people with cancer, including breast, colon, leukemia, ovary, pancreas, and stomach tumors, Aurora kinase malfunctions...
Source: Aging & Elder Health Week (2005-01-09)
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