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Albert Einstein College of Medicine
Genetic target found for lymphoma treatment
January 9th, 2005
Results from a preclinical study show that the gene designated Bcl-6 is an oncogene - that is, one with the potential to cause a normal cell to become cancerous - but that certain peptide inhibitors can in effect inactivate it, according to a study presented during the 46th annual meeting of the American Society of Hematology. Every year, more than 50,000 Americans are diagnosed with non-Hodgkin lymphoma. Diffuse large B-cell lymphoma (DLBCL) - the most common form of non-Hodgkin lymphoma and the focus of this study - comprises about a third of those cases. The Bcl-6 gene codes for a special protein, called a transcriptional repressor, which is a...
Source: Aging & Elder Health Week (2005-01-09)
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