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Fourth Military Medical University, Xi'an
DARPP-32 overexpressed in colorectal adenocarcinoma
April 10th, 2005
Research suggested that because DARPP-32 is overexpressed in colorectal adenocarcinoma, it might participate in the regulation of carcinogenesis. "Dopamine and cAMP-regulated phosphoprotein (DARPP)-32 is a phosphoprotein that is centrally involved in dopamine signaling pathways. It may play an important role in gastric tumorigenesis. Our aim is to investigate the expression of DARPP-32 protein in colorectal adenocarcinoma," scientists in the Peoples Republic of China reported. "The expression of DARPP-32 was evaluated by immunohistochemical SABC staining and Western blotting. DARPP-32 was specifically localized in colorectal epithelium. The...
Source: Aging & Elder Health Week (2005-04-10)
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