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Akdeniz University, Antalya
Interleukin-1 gene polymorphisms render susceptibility to Behcet disease
April 10th, 2005
Interleukin-1 gene polymorphisms render susceptibility to Behcet disease. According to a study from Turkey, "genetic factors that predispose individuals to Behcet disease (BD) are considered to play important roles in the development of the disease. The pro-inflammatory cytokine interleukin-1 (IL-1) has been implicated in the pathogenesis of BD. Our aim was to determine a possible association of specific polymorphisms of IL-1alpha, IL-1beta, and IL-1 receptor antagonist genes with susceptibility for BD." "We genotyped 72 patients with BD and 163 healthy controls for IL-1alpha-889, IL-1beta-511, and +3953 (nt5887) single-nucleotide polymorphisms...
Source: Aging & Elder Health Week (2005-04-10)
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