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Cardiovascular Research Unit, Rome
Nitrate therapy may be safely switched to trimetazidine therapy
April 10th, 2005
A recent report describes a comparison of trimetazidine plus sildenafil to chronic nitrates in the control of myocardial ischemia during sexual activity in patients with coronary artery disease. According to published research from Italy, "A large proportion of patients who have erectile dysfunction also have coronary artery disease (CAD). In these patients, nitrate therapy is a contraindication to the use of sildenafil. To assess whether the metabolic anti-ischemic agent, trimetazidine, is effective in controlling episodes of myocardial ischemia during sexual activity in patients who have CAD and use long-term nitrate therapy, we studied 38 men (57±6 years of...
Source: Aging & Elder Health Week (2005-04-10)
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