University of Illinois

3D femtosecond laser patterning of collagen used for directed cell attachment

Published in Aging and Elder Health Week, June 19th, 2005

A 3-dimensional femtosecond laser patterning of collagen was used for directed cell attachment.

"Three-dimensional micropatterned collagen scaffolds were fabricated by femtosecond laser ablation. An 800 nm, 45 fs Ti:Sapphire laser was used to create various 3D patterns in a collagen gel, including holes, lines and grids.

"An optimal collagen concentration was found for both substrate patterning and cell compatibility," scientists in the United States report.

"The threshold fluence for ablation of the scaffold was found to be 0.06 J/cm², and the morphology of the ablation craters was measured as a function of fluence,"...

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Source: Aging and Elder Health Week (2005-06-19)

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