Texas A&M University System Health Science Center
Natural antisense mRNAs inhibit hyaluronan biosynthesis and cell proliferation
Published in Aging and Elder Health Week, December 11th, 2005
"We report the identification of a natural antisense mRNA of hyaluronan synthase 2 that we have chosen to designate as HASNT (for HA synthase 2 antisense) in human and mouse. HASNT is transcribed from the opposite strand of the HAS2 gene locus and is represented by several independent expressed sequence tags in human."
"Portions of the mouse Hasnt gene were identified through an exon-trapping approach. Sequence conservation is extremely low between human and mouse HASNT, and it is not clear...
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