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Aging and Elder Health Week

Susan Hasty, Publisher

Table of Contents . . . January 29th, 2006

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Aging and Elder Health Week | Other Publications

Axonyx, Inc. - Alzheimer-focused drug developer receives notice related to Nasdaq minimum bid price rule

Berlex, Inc. - U.S. FDA approves osteoporosis indication for once-a-week hormone therapy patch

Bioenvision - Cancer cell-inhibiting drug shows significant activity in elderly leukemia patients

Genzyme Corp. - Extensive gene therapy assets acquired

Healthcare Coverage - North Carolina to expand community mental health services

Healthcare Economics - International research reveals proven ways to reduce drug costs

Medicare - Ancillary Care Management introduces InfuseD Medicare Part D solution

Medicare - Blue Cross Blue Shield of Michigan teams with retailer to educate consumers about Medicare programs

Medicare - Blue Cross Medicare Part D enrollees begin prescription drug coverage

Medicare - CanAmerica Global partners with Dusante LLC for Part D plans

Medicare - MemberHealth partners with SHPS for expansion of retiree health plans

Medicare - Study finds seniors in mid-Atlantic states have bewildering Medicare coverage choices

Medicare - U.S. HHS announces 21 million Medicare beneficiaries are covered for prescription drugs

Novartis Oncology - Letrozole as post-operative breast cancer therapy reduces recurrence, large study shows

Novartis Pharmaceuticals Corporation - Femara receives U.S. approval for new treatment indication

Aarhus University Hospital - Cytolytic effector pathways are up-regulated in rejected renal allograft tissue

Able Planet, Inc. - Hearing aid devices ready for retail distribution

Academy Medical Center, Amsterdam - K-ras mutation assays are useful in assessing extrahepatic biliary stenoses

Advancis Pharmaceutical Corp. - Sale of Keflex brand of cephalexin not completed in December

Affymax, Inc. - Synthetic peptide drug maker announces executive appointments

American Health Information Management Association - Plan outlined for promoting, using electronic records in long-term care settings

AtheroGenics, Inc. - Licensing and commercialization deal signed for atherosclerosis drug AGI-1067

Awards - Center for Surgical Weight Loss & Wellness designated as Center of Excellence

Baylor College of Medicine, Houston - Host immune response is impeded by Taenia crassiceps secreted enzymes

Behavioral Medicine - Florida behavioral healthcare provider licenses physiological substance abuse protocols

Beth Israel Deaconess Medical Center, Boston - Polyomavirus JC-specific cytotoxic T cells are present in the CNS of PML patients

Brigham & Women's Hospital, Boston - Younger women are more compliant with osteoporosis medications

CAS Medical Systems, Inc. - U.S. FDA grants 510(k) marketing clearance for near-infrared spectroscopy brain oximeter

Cancer Research UK & UCL Cancer Trials Center - Time to progression may be valuable surrogate marker in predicting breast cancer survival

Chang Gung Memorial Hospital - Trichloroacetic acid proves effective for low-grade vaginal intraepithelial neoplasia

Children's Hospital of Michigan - Vancomycin clearance differs by size of newborns relative to their gestational age

Chiron - Analysis recommends phase 3 trial of tifacogin for community-acquired pneumonia continue

Consorzio Mario Negri Sud, S. Maria Imbaro - Benefits of longer tamoxifen therapy were seen in younger estrogen receptor-positive women vs. older women

CryoLife, Inc. - Biomaterials, biosurgical-device company amends its bylaws

Dalhousie University - Researchers' data advance Streptococcus Vaccines research

Defense Research & Development Establishment, Gwalior - Monoclonal antibodies were generated to recombinant proteins of Yersinia pestis

Del Global Technologies Corp. - Imaging company acquires full ownership of its majority-owned Villa Sistemi Medicali subsidiary

Disease Management - "Electronic nurse" helps homebound patients stay out of hospital

Electronic Medical Records - Coalition America continues to see significant growth in EDI connectivity with its clients

Endo Pharmaceuticals, Inc. - Drugmaker files responses to FDA's approvable letters on NDAs for oxymorphone ER and IR tablets

Facilities - Survey of healthcare boards shows those discussing strategy, policy have higher performance

Freeman Hospital, Newcastle upon Tyne - At 60 min. cut-off rate, CPR duration is not linked to renal allograft outcome

GW Pharmaceuticals - U.S. FDA accepts investigational new drug application for Sativex

Genentech, Inc. - Supplemental BLA submitted for Avastin in relapsed metastatic colorectal cancer

Georgetown University Hospital - Embolization has emerged as accepted therapy for treatment of uterine fibroids

Georgetown University, Washington, DC - Gly972Arg was a common mutation in the Irs-1 gene in Turkish with diabetes mellitus

GlaxoSmithKline Inc. - Sitamaquine is efficacious for visceral leishmaniasis treatment in Kenya

Global Med Technologies, Inc. - Medical information company to recognize approximately $2.1M in one-time expenses

GlycoFi, Inc. - Merck enters into broad strategic alliance for research and development

Guided Therapy Systems - Miniaturized ultrasound arrays proposed for interstitial ablation and imaging

Harvard Men's Health Watch - Relationship of vitamin E and prostate cancer benefits not resolved, men's newsletter says

Harvard University - High plasma C-reactive protein in early pregnancy may be connected to preterm delivery

Heart Failure - Controlled trial looks at rehabilitative effects of exercise after heart failure

Herlev University Hospital - Bladder transitional cell tumors 9q, 11p and 14q LOH were under-represented

Hopital Ambroise Pare, Boulogne - Multidrug resistance proteins did not impair initial response of GIST to imatinib

Hopital Paris - Adolescent survivors of acute lymphoblastic leukemia suffer psychological and physical pain

Hospital General Universitario Gregorio Maranon, Madrid - MTB extrarespiratory strains infect macrophages more efficiently than respiratory strains

Howard Hughes Medical Institute - International research grants given to 28 scientists

INSERM U586, Toulouse - Methylamine but not mafenide mimics insulin-like activity and shows antidiabetic properties

IRCCS, Rome - Whole blood ELISA more specific than ELISPOT for active tuberculosis diagnosis

Influenza - Medical consulting company to assist with the California Influenza Surveillance Project

Information Technology - Arizona health system selects financial, clinical, administrative software suite

Integrated BioPharma, Inc. - Biopharmaceutical company names General James T. Hill director of InB: Biotechnologies

John P. Robarts Research Institute, London - BM cell population migrates to skeletal muscle via hepatocyte growth factor/c-met axis

John Peter Smith Hospital, Fort Worth - Split orbicularis myomucosal flap used for lower lip reconstruction

John Radcliffe Hospital, Oxford - Article reviews therapeutic immunization strategies to control HIV-1

Karolinska Institute - A better understanding of the pathways governing apoptosis may yield new targets for therapy

Leiden University - Dexamethasone inhibits neointima formation but is linked to adverse vascular changes

Leiden University - UV-induced mutant p53 and skin tumors analyzed by mutation spectra and induction kinetics

Lexicon Genetics Incorporated - Two milestones totaling $20 million in payments reached in Genentech alliance

Lifeline Biotechnologies, Inc. - Carlo Micheletti completes sales management team at medical technologies company

M.D. Anderson Cancer Center - Peritoneal mesotheliomas and serous carcinomas diagnosed by immunohistochemistry

MacroChem Corporation - Drug delivery company announces $2.5 million private placement with institutional investors

Mayo Clinic College of Medicine - Immune system/bone interaction may give insight to osteoporosis pathophysiology

MedMira Inc. - Diagnostics company renegotiates $2.3 million convertible debenture

Medical Research Council, Lanark - Reports add new data to Hepatitis C Virus research

MedicineLodge, Inc. - Stryker Spine purchases minimally invasive spinal access technology

Medicis Pharmaceutical Corp. - Inamed announces mutual termination of merger agreement with dermatology-focused drug maker

Memorial Hospital of Rhode Island - Review assesses prevalence of complications related to metformin use in diabetes treatment

Memorial Sloan-Kettering Cancer Center - Effect of epidermal growth factor receptor inhibitors on gliomas studied

Memorial Sloan-Kettering Cancer Center, New York - Sickle cell disease corrected in human models using stem cell-based gene therapy

Mergers & Acquisitions - Brookdale acquires a previously leased six-facility portfolio

Mergers & Acquisitions - Health Fitness Corp. acquires HealthCalc Network, Inc.

Ministry of Health & Social Development of the Russian Federation, Moscow - Induced expression of melittin suppresses Chlamydia and Mycoplasma infections

Molecular Diagnostics, Inc. - Cancer screening systems maker changes its name to CytoCorp

Mount Sinai School of Medicine, New York - Data advance knowledge in Cancer Therapy research

Nagoya City University Medical School, Aichi - ErbB2 mutations are rare in Japanese patients with lung cancer

Netherlands National Institute of Public Health & Environment - VNTR and FliP are rapid and discriminatory Mycobacterium tuberculosis typing methods

Northwestern University, Chicago - The MCT-1 oncogene promotes tumor angiogenesis and blocks apoptosis

Norway Institute of Transport Economics - Study identified driver health conditions that signify crash risk factors

Osaka University - Clinical efficacy of cancer immunotherapy targeting WT1 protein should be clarified

Osmangazi University, Eskisehir - Serum Cys C and urinary enzymes may be screening markers for renal dysfunction in diabetics

Osped CSS, San Giovanni Rotondo - MDR1 polymorphisms are not associated with inflammatory bowel disease

Patient Compliance - Patients are compliant with statin therapy for 3 years regardless of gender or age

Personnel - Public health scholar Susan C. Scrimshaw named president of Simmons College

Personnel - Steven Glass, CPA, named chief financial officer of Cleveland Clinic Health System

Pharmacogenetics - Genetics may influence efficacy and safety of commonly prescribed drugs

Pharsight Corp. - Software maker reports expanding use of DMX

Progenics Pharmaceuticals, Inc. - Pharma company acquires royalty and milestone rights for methylnaltrexone

Purdue University, West Lafayette - Engineers design nutrition delivery system for Kenyan AIDS victims

Purdue University, West Lafayette - Researchers curb activity of "watchdog" protein that slows spread of genetically predisposed cancer

ResMed, Inc - Respiratory disorders company appoints head of European operations and CFO

SUNY College Oswego - Potent background stressor can heighten CV responses

Schering-Plough Corporation - Combination treatment for chronic hepatitis C granted marketing approval in Japan

Sepracor Inc. - Hydrofluoroalkane metered-dose inhaler available by prescription for asthma, COPD

Shire Pharmaceuticals, Inc. - U.S. FDA issues approvable letter for transdermal patch to treat ADHD in children 6-12

Shire plc - New drug application filed with U.S. FDA on mesalamine treatment for ulcerative colitis

Smith & Nephew Orthopaedics - Orthopedic devices company launches device for hindfoot degeneration, trauma

St. James Hospital, Dublin - Vitamin C enhanced chemosensitization of esophageal cancer cells

Swedish Medical Center, Seattle - Prepregnancy physical activity is associated with decreased risk of preeclampsia

Taiwan Center of Disease Control - Antigenic divergence of B. pertussis circulating isolates has evolved over time

Targanta Therapeutics Inc. - Discovery of new class of agents to target Staphylococcus aureus announced at meeting

Temple University, Philadelphia - Age-related memory deficits were reversed by galantamine treatment in murine model

Thomas Jefferson University - Finding enables scientists to refine vaccine against rabies

Tibotec Pharmaceuticals Ltd. - Pharma company submits new drug application to U.S. FDA for HIV-1 treatment

Tohoku University, Sendai - Studies describe new findings in Diabetes Pathogenesis research

Tokyo Medical & Dental University - Risk of radiation-induced cancer in SCH patients deemed small

U.S. National Institutes of Health - Primer removal not a necessary component of HIV-1 reverse transcription

Universidad Austral de Chile, Valdivia - Pharmacokinetics of cyclosporine is not affected by gender of renal transplant patients

Universidad del Valle, Cali -  P. vivax Pvs25 recombinant protein blocks parasite transmission

Universitatsklinik, Bochum - Pain treatment analyzed among patients with incurable malignant tumors

University Children's Hospital, Zurich - Further studies are needed to safely treat arterial thromboembolic events in pediatric patients

University of Bergen - New form of diabetes described

University of Bonn - Recent findings illuminate research in Transplant Medicine

University of Calgary - Study examines new pathways linking cholestatic liver disease to central nervous system changes

University of California, Berkeley - Alcohol use is a risk factor for acquiring HIV infection from female sex workers

University of California, Los Angeles - PBK/TOPK is a marker for transiently amplifying neural progenitors in subependymal zone

University of California, San Francisco - Ischemic preconditioning improved transplantation survival from 25 to 88% in rat model

University of California, San Francisco - Neurocardiogenic injury may be due to excess norepinephrine

University of Cambridge - Activin/Nodal and FGF pathways cooperate to maintain ESC pluripotency

University of Chile, Santiago - Prophylactic thyroidectomy used to treat hereditary medullary thyroid carcinoma

University of Cincinnati - Recombinant factor VIIa is potentially useful for intracerebral hemorrhage

University of Cologne - Inhibited nuclear translocation overcomes apoptosis signaling defects in B-cell malignancies

University of Dundee - Review investigates the influence of leptin on hippocampal synaptic plasticity

University of Heidelberg - Notch signal blockade halts pancreatic cancer neurovascular progression

University of Heidelberg - Protein overexpression influences pancreatic ductal adenocarcinoma cell growth

University of Kiel - Findings in oncology provide new insights

University of Leeds - Complement C3 and CRP levels are elevated in patients with stable coronary artery disease

University of London University of College - Material and morphological properties of bone collagen can be analyzed in situ

University of Pennsylvania - HIV-1 VPR protects against lethal superantigen challenge while maintaining T cell levels

University of Pennsylvania - Low-carbohydrate diet is not more cost-effective than standard diet for weight loss

University of Pennsylvania - Obtaining refills via pill organizers dispensed by pharmacist improves HAART adherence

University of Prince Edward Island - New research in the area of diagnostics detailed

University of Queensland - Exercise increases pulse pressure amplification, aortic stiffness

University of Queensland - Researchers identify large tracks of human genome that lack transposable genetic elements

University of Texas, Houston - Calcitonin gene-related peptide localization is similar to sarcolemmal L-type calcium channel

University of Toronto - Urgency scale inclusion in coronary angiography queue management may decrease mortality

University of Tsukuba, Ibaraki - Transgenic rabbits model the features of Kasabach-Merritt syndrome

University of Turin - Anti-HER-2 DNA vaccine protects against squamous cell carcinomas

University of Ulsan, Seoul - AMPK activation by alpha-Lipoic acid prevents endothelial dysfunction in obese rats

University of Utrecht - Radiation treatment should be administered within 2 days of surgery to reduce keloid recurrence

University of Western Australia - Local reactions to diphtheria-tetanus-acellular pertussis vaccine are Th2-associated

University of Wisconsin - Delivery of naked plasmid DNA into muscle corrects hyperbilirubinemia

University of Wisconsin - Tat-specific CD8 cells suppress SIV replication more effectively than Gag-specific cells

Viking Systems Inc. - Laparoscopic 3-D vision systems maker announces closing of $3 million bridge financing

Virginia Commonwealth University - Study suggests depression more commonly inherited in women than men

Walter and Eliza Hall Institute, Melbourne - Faults in newly discovered breast stem cells may lead to tumors

Washington University, St. Louis - Research add new data to Nosocomial Infections body of knowledge

Weight Watchers International, Inc. - Online weight management company redeems remaining minority interest for $304.8 million

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