Published in Aging and Elder Health Week, June 4th, 2006
"Because NFAT has been implicated in TNF production as well as osmoregulation and salt and water homeostasis, we addressed whether CaR-mediated TNF production in medullary thick ascending limb (mTAL) cells was NFAT dependent," wrote H.I. Abdullah and colleagues, New York Medical College.
"TNF production in response to addition of extracellular Ca2+ (1.2 mM) was abolished in mTAL cells transiently transfected with a dominant-negative CaR construct (R796W) or...
Want to see the full article?
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Aging and Elder Health Week
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.