Neuropathy

Denervated skeletal muscles still able to generate new capillaries

Published in Angiogenesis Weekly, March 15th, 2002

by Sonia Nichols, senior medical writer - Skeletal muscles that fall victim to denervation are still able to generate reparative capillaries, according to a University of Michigan, Ann Arbor study.

In fact, angiogenesis markers can be detected in denervated skeletal muscles long after nerve injury has occurred, signaling muscle atrophy does not automatically preclude neovascularization in affected tissues, the researchers reported in Microvascular Research.

The University of Michigan investigators, headed by E.I. Dedkov, studied hindlimb skeletal muscles 25 months after denervation in several rats. Most of the rats experienced deterioration...

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Source: Angiogenesis Weekly (2002-03-15)

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