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Angiogenesis Weekly

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Urology



Piroxicam and chemotherapy combine to diminish urinary bladder cancer



April 11th, 2003

Piroxicam and chemotherapy combine to diminish urinary bladder cancer.

"The objectives of this study were to determine the antitumor activity and toxicity of a cyclooxygenase inhibitor (piroxicam) combined with cisplatin chemotherapy in dogs with naturally-occurring, invasive transitional cell carcinoma (TCC) of the urinary bladder and to determine the effects of this treatment on prostaglandin E-2 concentration, tumor cell proliferation and apoptosis, and angiogenesis," wrote S.I. Mohammed and colleagues, Purdue University, Department of Veterinary Clinical Science.

"Pet dogs with naturally-occurring invasive TCC underwent complete tumor staging...


Source: Angiogenesis Weekly (2003-04-11)

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