Angiogenesis

New angiogenesis research from University of Sao Paulo discussed

Published in Angiogenesis Weekly, December 14th, 2007

According to recent research from Sao Paulo, Brazil, "Angiogenesis is a fundamental process that allows tumor growth by providing nutrients and oxygen to the tumor cells. Beyond the oxygen diffusion limit from a capillary blood vessel, tumor cells become apoptotic."

"Angiogenesis results from a balance of pro- and anti-angiogenic stimuli. Endogenous inhibitors regulate enzyme activities that promote angiogenesis. Tumor cells may express pro- angiogenic factors and hydrolytic enzymes but also kinin-degrading oligopeptidases which have been investigated. Angiogenesis induced by B16F10-Nex2 melanoma cells was studied in a co-culture with HUVEC on Matrigel. A stimulating...

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Source: Angiogenesis Weekly (2007-12-14)

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