Life Sciences

Research from L.S. Xu and colleagues has provided new data on life sciences

Published in Angiogenesis Weekly, March 27th, 2009

"The R-ras gene encodes a small GTPase of the ras family that is closely related to H-ras and K-ras. Unlike the prototypic ras genes, the disruption of the R-ras gene in mice results in enhanced angiogenesis in tumor implants and sustained neointimal hyperplasia in response to arterial injury, indicating the in vivo role of R-ras as a negative regulator of vascular proliferation," scientists in the United States report.

"R-ras is abundantly expressed in normal mature blood vessels but significantly down-regulated in pathologically regenerating vasculature. In this study, we investigated the roles of cis-acting elements in the transcription of the human R-ras gene, as...

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Source: Angiogenesis Weekly (2009-03-27)

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