Angiogenesis Weekly
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Gastroenterology
Research results from University of Louvain update knowledge of gastroenterology
June 19th, 2009
"IL-9 contributes to lung inflammatory processes such as asthma, by promoting mast cell differentiation, B cell activation, eosinophilia, and mucus production by lung epithelial cells. The observation that IL-9 overexpressing mice show increased mast cell numbers in the intestinal mucosa suggests that this cytokine might also play a role in intestinal inflammation," scientists in Brussels, Belgium report. "In colons from IL-9 transgenic mice, the expression of Muc2, a major intestinal mucin gene, was up-regulated, together with that of CLCA3 chloride channel and resistin like alpha, which are goblet cell-associated genes. Additional IL-9 up-regulated genes were...
Source: Angiogenesis Weekly (2009-06-19)
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