Angiogenesis Weekly
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Life Sciences
New life sciences findings from X.C. Pi and co-researchers published
June 19th, 2009
According to recent research published in the journal Proceedings of the National Academy of Sciences of the United States of America, "The chemokine stromal cell-derived factor-1 alpha (SDF-1 alpha) is a pivotal player in angiogenesis. It is capable of influencing such cellular processes as tubulogenesis and endothelial cell migration, yet very little is known about the actual signaling events that mediate SDF-1 alpha-induced endothelial cell function." "In this report, we describe the identification of an intricate SDF-1 alpha-induced signaling cascade that involves endothelial nitric oxide synthase (eNOS), JNK3, and MAPK phosphatase 7 (MKP7). We demonstrate...
Source: Angiogenesis Weekly (2009-06-19)
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