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Angiogenesis Weekly

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Life Sciences



University of Saarland reports research in life sciences



June 19th, 2009

"Wound infections caused by Staphylococcus aureus are associated with significant morbidity and mortality. The staphylococcal extracellular adherence protein (Eap) has been shown to delay wound healing by interfering with host defense and angiogenesis, yet the expression of Eap in the human wound is required to exert these functions," scientists in Homburg, Germany report.

"A protocol was developed to determine eap transcription levels in vivo (human wounds) relative to those in vitro. In parallel, isolates derived from positive blood cultures were analyzed for eap transcription. Transcription of eap was found in vivo as well as in vitro for all isolates, with eap...


Source: Angiogenesis Weekly (2009-06-19)

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