Angiogenesis Weekly
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Angiogenesis
Data from University of Pennsylvania provide new insights into angiogenesis
November 6th, 2009
According to recent research from the United States, "A precise balance exists between the actions of endogenous glucocorticoids ( GC) and retinoids to promote normal lung development, in particular during alveolarization. The mechanisms controlling this balance are largely unknown, but recent evidence suggests that midkine (MK), a retinoic acid-regulated, pro-angiogenic growth factor, may function as a critical regulator." "The purpose of this study was to examine regulation of MK by GC and RA during postnatal alveolar formation in rats. Newborn rats were treated with dexamethasone (DEX) and/or all-trans-retinoic acid (RA) during the first two weeks of life. Lung...
Source: Angiogenesis Weekly (2009-11-06)
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