Anti-Infectives Week
Susan Hasty, Publisher
Table of Contents . . . September 29th, 2003
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Anti-Infectives Week | Other Publications
Anti-Infectives - Genome of bacteriophage infecting Pseudomonas aeruginosa reported
Antibiotics - GABA(A) receptor blockade underlies cephalosporin-induced convulsions
Antibiotic Resistance - Ingredient in domestic detergent may not be culprit after all
Antimicrobials - Pyrimidinone antibiotics exhibit improved antibacterial spectrum
HIV Prevention - Phase I testing of HIV microbicide initiated
Peritoneal Sepsis - EDU in HA/CMC gel reduces surgical infection
Anti-Infectives - Ofloxacin receives FDA approval
Antibiotics - Generic pharmaceutical company licenses clarithromycin XL
Antibiotics - Linezolid does not impair polymorphonuclear neutrophils activity
Antibiotics - Milestone achieved in development of peptide deformylase inhibitors
Antifungal Therapy - Assay for itraconazole drug monitoring developed
Antimicrobial Peptides - Human intestinal mucosa is rich in antibacterial, antifungal peptides
Bacterial Growth - Catecholamines enhance growth of E. coli but not some other bacteria
Biostatistics - Subgroup analysis can be planned for with a useful method in clinical trials
Botulism - Joint venture wins $11M award to expedite production of botulinum vaccine
Candida Albicans - Level of disease activity, oral or vaginal location induce different enzymes
Cell Transport - Transport by multidrug resistance-associated protein 3 investigated
Co-stimulatory Molecules - ICOS may be involved in Peyer patch expansion and IgA, IgG production
Collaborations - Chemistry deal signed for development of small-molecule compounds
Cytomegalovirus - Atherosclerosis patients have CMV infection in vessel walls
Drug Development - Fosmidomycin disrupts plasmodial DOXP pathway
Drug Development - Novel carbapenem has improved anti-MRSA activity
Enterococcus Faecalis - The serotype 2 polysaccharide of E. faecalis is made during log phase
Epilepsy - Antiepileptic drugs can alter and be altered by other drugs
Finance - Funding will help company prepare for NDA filing for SnET2
Gynecology - Staphylococcus levels on tampons may be higher than previously reported
Hepatitis C Therapy - Antivirals prevent lymphoproliferative disease in chronic hepatitis C patients
Hepatology - Aeromonas infection of the hepatobiliary system reported
Human Parechovirus - HPEV-1 has different replication complex than other picornaviruses
Infectious Disease Therapy - Mechanisms of atovaquone-induced cytochrome bc1 complex inhibition characterized
Malaria Therapy - P. falciparum plasmepsin inhibitors show promise
Malaria Therapy - Antimalarial imidazo[2,1-a]isoindole derivatives have potent activity
Malaria Therapy - Artemisinins target plasmodial SERCA protein
Malaria Therapy - Efflux pump mediates P. falciparum resistance to chloroquine
Malaria Therapy - Quinoline-based inhibitors of plasmodial PfA-M1 developed
Mycobacterium Marinum - Fish tanks can be a source of M. marinum skin infection
Personnel - Dr. Louis W. Sullivan and Marc L. Preminger elected to biopharma company board
Pneumonia - Levofloxacin-resistant pneumococci appear easily, persist after initial therapy
Pneumonia Diagnostics - Urinary antigen test detects S. pneumoniae after antibiotic treatment started
Proteomics - Protein from Streptomyces cacaoi is penicillin-binding
Rickettsia - LepB gene for signal peptidase is similar in R. rickettsii, R. typhi
Septicemia - Sepsis is best treated when bacterial-host molecular interactions are considered
Sexually Transmitted Disease - Gemifloxacin is active against Neisseria gonorrhoeae with gyrA mutation
Streptococcal Infections - Toxic shock syndrome may be treatable with IVIG therapy
Urinary Tract Infection - Early completion of patient recruitment in phase II clinical trial of doripenem
Urinary Tract Infections - Ciprofloxacin GR is as effective as Cipro
Ventilator-associated Pneumonia - FDA grants fast track designation for Iseganan
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