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Anti-Infectives Week

Susan Hasty, Publisher

Table of Contents . . . October 27th, 2003

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Anti-Infectives Week | Other Publications

Drug Development -  S. cerevisiae gene expression profiling clarifies drugs' antifungal activity

Pseudomonas - Researchers find promising new avenues for treating infections

Antibiotics - Ribosome binding thiazole antibiotics exhibit contrasting activities

Antimicrobial Resistance - Multidrug transporters of E. coli play role in resistance to beta-lactams

Drug Resistance - Resistance patterns of pneumococcal diseases in adults with HIV reported

HIV Therapy - Antiretroviral therapy reduces HIV-1 transmission when started after childbirth

AIDS Research - U.S.-Russian initiative to intensify cooperation in fight against disease

Antibiotic Discovery - Mpex signs agreement with discovery chemistry company

Antibiotics - Licensing agreement reached for broad-spectrum antibiotic

Antifungals - Immunocompromised pediatric patients can be treated safely with caspofungin

Antimicrobial Proteins - Human parotid secretory protein is an antibacterial in saliva and parotids

Antimicrobial Resistance - Resistance to tiamulin caused by mutation of ribosomal protein L3

Antipneumococcal Activity - LPS binding protein also binds non-lipid sections of pneumococcal cell wall

Collaborations - Library license agreement signed for discovery of therapeutic antibodies

Complementary and Alternative Medicine - Ayurvedic medicinal Withania somnifera appears to relieve chronic stress

Complementary and Alternative Medicine - Many different compounds isolated from Plantago are immunostimulatory

Dermatology - MBI 594AN phase IIb acne trial complete

Drug Development - Novel cephalosporin shows promise

Drug Development - Sulfanylbenzoic acid derivatives of salicylanilides have enhanced antimycobacterial activity

Ear Infections - Chiropractic approach to ear infections described

Food Safety - Lactate dehydrogenase immunoassay marks when beef cooking eliminates bacteria

Fungal Infections -  Tinea infections may require topical antifungals or systemic therapy

Gynecology - Cure for salpingitis often necessitates combination therapy

HIV Prevention - $10M in milestone funding to be used for HIV fusion inhibitor

HIV Therapy - Preclinical testing of second generation HIV viral entry inhibitor expanded

HIV Vaccine - Phase II study of Remune with HIV-infected patients begins in Italy

HIV/AIDS Lipodystrophy - Predictors of HIV dyslipidemia identified

HIV/AIDS Theapy - CCR5-disrupting molecules can prevent HIV infection

HIV/AIDS Therapy - IL-15 levels may predict STI outcome in chronic HIV patients

HIV/AIDS Therapy - Neural networks can help identifiy HIV lopinavir resistance mutations

HIV/AIDS Therapy - Quadruple antiretroviral regimens compared

HIV/AIDS Therapy - Rapamycin downregulates CCR5 and heightens anti-HIV chemokine levels

HIV/AIDS Therapy - Ritonavir-boosted saquinavir and indinavir have similar efficacy

Healthcare Economics - Study assesses the hidden costs of administering intravenous antibiotics

Immunology - HIV protein attacks body's innate protection system that could prevent virus' replication

Immunosuppression - Radiotherapy patients given zinc supplementation have fewer oral infections

Immunosuppression Risk - Crystallography reveals structure of acyclovir-bound HsPNP

Infection - StaphVAX confirmatory-phase-III trial ahead of schedule

Infectious Disease - CDC partners with University of Liverpool for research alliance

Infectious Disease - Epidemic cholera strains reemerging in Bangladesh

Infectious Disease Therapy - Co-trimoxazole may be effective against MRSA

Inflammatory Diseases - Crohn disease etiology has not been found; there are many treatment options

Malaria Therapy - Malarial hemozoin formation elucidated

Malaria Therapy - Paroxysm serum from P. vivax infection blocks P. falciparum maturation

Mergers and Acquisitions - Net Force gains controlling interest in vaccine company in Mainland China

Mergers and Acquisitions - Nutra Pharma Corp. to acquire diagnostic-kit company

Nanobacterial Infections - Study will evaluate nanobacterial endotoxin in patients undergoing angioplasty

Neonatology - Company launches family of neonatal oxygen-delivery hoods

Otorhinolaryngology - PLUNC proteins may be antibacterials that protect mouth, nose, lung epithelium

Outbreaks -  Candida rugosa may be emerging human pathogen

Psoriasis - New light unit assembly expands phototherapy applications

Seborrheic Dermatitis - Malassezia yeasts may be responsible for seborrheic dermatitis; antifungals work

Sexually Transmitted Disease -  Chlamydia trachomatis regulates genes that reinforce its viability

Staphylococcal Infection - High clonal diversity seen in Norwegian MRSA isolates

Stock Market - Purification company receives NASDAQ notice of noncompliance

Transfusion Medicine - MDS Nordion licenses x-ray blood irradiation technology

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