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Anti-Infectives Week

Susan Hasty, Publisher

Table of Contents . . . April 12th, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Anti-Infectives Week | Other Publications

HIV/AIDS Drug Resistance - Development of indinavir resistance can be insidious

Nosocomial Infection - Hairpin probe and gold gets bad bugs glowing

Bacteriology - Class of enzymes offers new way to kill superbugs

Infectious Disease - Oral mucosa defends against Candida albicans infection in humans

Pneumonia - Giving antibiotics within 4 hours of arrival at a hospital improves outcomes

Anthrax - ETI-204 prevents death from anthrax exposure in animals

Anti-Infectives - Anti-PRSP efficacy of meropenem evaluated

Anti-Infectives - Caspofungin effective for pediatric cancer patients, bone marrow recipients

Anti-Infectives - Extended interval gentamicin dosing safe for preterm infants

Anti-Infectives - Gemifloxacin inhibits cytokine release by LPS-stimulated monocytes

Antibiotic Resistance - Methods detects trace levels of swine antibiotics in groundwater

Antimicrobial Drug Resistance - Resistance rates of Salmonella enterica serotype Typhi in S. Korea determined

Antiseptics - Three-year contract signed for FDA-approved waterless surgical hand prep

Arthritis Therapy - Infliximab can induce lupus erythematosus-like eruptions in RA patients

Atherosclerosis - Chlamydial LPS-specific IgG antibodies useful as sign of lesion infection

Business & Finance - Biopharmaceutical reports increase in cash position and total shareholder equity

Business Update - Immtech continued to prepare for commercialization

Carcinogens - Some bacterial toxins could cause cancer

Chronic Hepatitis C - Interferon improves survival in HCV patients by negating liver-related death

Collaborations - Exclusive deal signed for new sepsis marker

Disease Transmission - Project aims to develop microbicides to protect women against HIV

Drug Development - Novel HIV fusion inhibitor T-1249 safe, effective in early trials

Drug Development - Pegylated IFN-alpha effective as SARS prophylaxis in macaques

Finance - Biotechnology company announces adoption of 10b5-1 trading plans

Finance - Company announces $7.29 million private placement with institutional investors

Finance - Diagnostics company reports 2003 net revenues increase 27.7% from prior year

Finance - Protein-based biopharmaceutical company reports 2003 financial results

HIV/AIDS - Applications submitted for fixed-dose coformulation of Viread and Emtriva

HIV/AIDS - Health Canada official to join global HIV partnership

HIV/AIDS Cancer - Anti-HHV-8 therapy effective against multicentric Castleman disease

HIV/AIDS Cancer - Bone marrow features in AIDS patients characterized

HIV/AIDS Dyslipidemia - Bone mineral loss frequent in female patients during HAART

HIV/AIDS Epidemiology - "Dipping" may throw off conventional measures of sexual behavior

HIV/AIDS Genomics & Genetics - Effect of within-patient HIV mutation on population-level evolution clarified

HIV/AIDS Genomics & Genetics - Recombination dynamics of HIV genome determined

HIV/AIDS Immune Control - Interaction between Leishmania and HIV clarified

HIV/AIDS Neuropathology - Effects of HAART on CNS disorders elucidated

HIV/AIDS Pathogenesis - Thiol/disulfide exchange needed for R4 HIV T-cell fusion during viral entry

HIV/AIDS Policy - Failures of Russian AIDS policy dissected

HIV/AIDS Public Health - Participatory action research program has promising results in Philippines

HIV/AIDS Therapy - HIV-infected cells have heightened vulnerability to electrical damage

HIV/AIDS Therapy - Lipid profiles induced by different antiretroviral drugs characterized

HIV/AIDS Tuberculosis - Effects of HIV/TB coinfection of mothers in poor areas clarified

HIV/HBV Coinfection - Treatment for HBV infection in HIV patients reviewed

Immunology - Potential benefits of G-CSF treatment for critically ill reviewed

Infection - Bowel management systems found to help fight hospital-acquired infections

Infectious Disease - Primary cutaneous cryptococcosis reported in elderly immunocompetent man

Influenza - Hope for flu fight progresses as researchers crack communication

Malaria Drug Resistance - Rate of atovaquone, proguanil resistance mutations in Ghana determined

Mergers & Acquisitions - Hemispherx completes acquisition for worldwide rights to Alferon N

Microbiology - Bacteria play rock-paper-scissors

Mosquito-Borne Disease - Aea-TMOF shows promise for mosquito vector control

Mosquito-Borne Disease - DEET efficacy, tolerability confirmed in Pakistan refugee camp

Mosquito-Borne Disease - KBR 3023 is comparable to DEET for antimosquito protection

Obstetrics - Bacterial link to preterm birth substantiated in mice studies

Onychomycosis - Company initiates clinical trial of EcoNail antifungal lacquer

Patents - Company obtains additional U.S. patents on antibody technologies

Sexually Transmitted Disease -  Mycoplasma genitalium causes urogenital problems in both men and women

Staphylococcus Aureus - Clinical outcomes registry launched to improve patient management

Staphylococcus Aureus - Levels of MRSA among children have risen rapidly in 10 years

Surgical Scrub - TRISEPTIN surgical scrub selected for military medical treatment facilities

Transfusion Medicine - Hepatitis C virus variants may not associate with extent of pathogenesis

Tuberculosis - Cough-generated M. tuberculosis aerosols may aid TB study

Tuberculosis Drug Resistance - PZase-negative TB strains with wild-type pncA reported

Urinary Tract Infection - Positive phase III clinical trial results for Ciprofloxacin reported

Urinary Tract Infections - National survey uncovers widespread misconceptions about UTIs

Vector-Borne Disease - Mosquitoes vs. malaria: How we can win the fight

Virology - HCV superinfections have differential effects on HBV-related cirrhosis

Virology - Hepatitis B virus DNA in culture can be analyzed for life cycle dynamics

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