Mosquito-Borne Disease

Aea-TMOF shows promise for mosquito vector control

Published in Anti-Infectives Week, April 12th, 2004

Aea-Trypsin Modulating Oostatic Factor (TMOF) appears to be an effective means of controlling mosquito vector populations.

According to recent research from the United States, "[t]rypsin and chymotrypsin-like enzymes were detected in the gut of Aedes aegypti in the four larval instar and pupal developmental stages."

"Although overall the amount of trypsin synthesized in the larval gut was 2-fold higher than chymotrypsin, both enzymes are important in food digestion," noted D. Borovsky and coauthors at the University of Florida.

Feeding Aea-TMOF "to Ae. aegypti and Culex quinquefasciatus larvae inhibited...

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Source: Anti-Infectives Week (2004-04-12)

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