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Anti-Infectives Week

Susan Hasty, Publisher

Table of Contents . . . August 23rd, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Anti-Infectives Week | Other Publications

Anti-Infectives - Antibacterial mechanisms of MccJ25 characterized

Antiviral Therapy - Novel bicyclic sugar modified nucleosides do not show antiviral activity

Complementary & Alternative Medicine - Essential oils from coniferous trees are antibacterial and antifungal

Drug Development - U.S. FDA approves drug application for corticosteroid and antifungal lotion

HIV/AIDS Research - Novel CCR5 antagonists have anti-HIV activity

Anthrax - Company awarded NIH grant to develop anthrax vaccine

Antibiotic Resistance - Agreement inked for Bridged Bicyclic Ketolide antibiotic in Japan, East Asia

Antimicrobial Susceptibility - Antimicrobial occurrence and susceptibility determined in Sfax-Tunisia isolates

Antiretroviral Therapy - Antiretroviral emtricitabine (FTC) has low toxicity in HIV-infected patients

Antiretroviral Therapy - Efuvirtide should still be considered outside of its optimal parameteters

Antiretroviral Therapy - Foscarnet-NNRTI conjugates potent activity against foscarnet-resistant HIV-1

Antiretroviral Therapy - Mental illness and sociological factors impact antiretroviral adherence

Antiretroviral Therapy - Peptides isolated from tropical plants inhibit HIV-1 cytopathic effects

Antiretroviral Therapy - Peptides that bind to potent HIV-inactivating protein cyanovirin-N characterized

Antiretroviral Therapy - Rapeseed protein hydrolysates new source of HIV protease inhibitors

Antiretroviral Therapy - Ritonavir/ritonavir-boosted saquinavir does not effect saquinavir action

Antiretroviral Therapy - beta-D-3'-fluoro-2',3'-unsaturated nucleosides active against HIV

Autoimmune Diseases - Understanding T-cell activation in vivo could mean better treatment, prevention

Bacterial Infection - Methicillin-resistant S. aureus infections are epidemic in injection drug users

Bacterial Infection - Toxic shock-like syndrome due to group C streptococcus is fatal

Breastfeeding - Ethiopia's health ministry, UNICEF join forces to promote safe breastfeeding

Business & Finance - New share repurchase authorized by health science technologies board

Business & Finance - Pharmaceuticals company reports second quarter 2004 results, clinical update

Candida Infection - Length of intensive care independent risk factor for Candida infection

Collaborations - Agreement signed with Asian partner for Intercept blood system for platelets

Complementary & Alternative Medicine - Maggots make medical comeback for healing wounds

Drug Delivery - Agreement inked to sell Soriatane to select international markets

Enterobacter Infection -  E. Sakazakii is rare cause of neonatal septicemia or meningitis in VLBW infants

Foot & Mouth Disease - Foot-and-mouth disease risk associated with proximity to infected premises

Fungal Infections - FDA approves ANDA for Fluconazole Injection mini bags

HIV/AIDS Assay - Modified HIV genotype assay increases limit of detection below 1000 copies/ml

HIV/AIDS Research - CD4 expression allows infection of CD8 cells by HIV

HIV/AIDS Research - Cerebral synthesis of complement factors strongly upregulated in SIV infection

HIV/AIDS Research - HIV Tat protein prevents long-term potentiation in hippocampal CA1 region

HIV/AIDS Research - HIV replication occurs predominantly in Th1 cells

HIV/AIDS Research - Indinavir is only HIV-1 proteinase inhibitor that inhibits HTLV-1 proteinase

HIV/AIDS Research - Novel cyanobacterial protein MVL inhibits HIV-1 envelope-mediated cell fusion

HIV/AIDS Research - Primary T cell HIV infection determined by tunable T cell activation thresholds

HIV/AIDS Research - SAR and pyrrolidineacetic acid derivatives are potent HIV CCR5 antagonists

HIV/AIDS Transmission - HLA-B allele-sharing associated with accelerated HIV transmission

HIV/AIDS Treatment - Perceived stress mediates coping effects of HIV-infected women on HAART

HIV/AIDS-Associated Dementia - HIV associated neurodegeneration requires p53 in neurons and microglia

HIV/AIDS-Associated Infection - Hospital-acquired candidemia still a severe complication in advanced AIDS

HIV/AIDS-Associated Infection - L-AmB effective as secondary prophylaxis for leishmaniasis in HIV infection

HIV/AIDS-Related Pneumonia - CD4 T-cell subsets depressed in acute stage of HIV-related S. pneumoniae

Helicobacter Pylori - Basophils infiltrate human gastric mucosa at sites of H. pylori infection

Hepatitis - High response rates achieved for treatment of hepatitis C and HIV

Hepatitis C Vaccine - Monoclonal antibody to hepatitis C glycoprotein blocks viral infectivity

Herpesvirus - HHV-8-specific antibodies detected in HSCT recipients by peptide-based EIA

Herpesvirus Infection - KS associated with high pretransplant prevalence of HHV-8 among Africans

Immunology - School nurses urge back-to-school tetanus immunizations for adolescents

Infection - Anti-infective drug maker reports loss of $0.37 per share

Infectious Disease - Brazilian TT virus isolate closely related to SEN virus-F

Influenza Strains - Cross-protection explains single influenza illness peaks in temperate climates

Influenza Vaccine - Chemiluminescent neuraminidase assay monitors drug susceptibility

Influenza Virus - Compatibility convergence between H1/N2 components of two influenza A subtypes

Influenza Virus - Influenza A virus NP sequence variation associated with escape from CTLs

Influenza Virus - Sensitive RT-PCR detects influenza A virus and amantadine-resistant isolates

Joint Replacement - Utility of prophylactic antibiotic bone cement reviewed

Patents - DNA-expression company files for patents for antibacterials, antifungals

Retroviral Research - HTLV-1 budding requires both Nedd4 and Tsg101

Retrovirolgy - Fusion of first 54 amino acids of Vpu to Env results in virus maturation

Risk Factor - Genes encoding toxins of diverse S. flexneri isolates identified

SARS Vaccine - Domain in SARS coronavirus spike protein induces neutralizing antibodies

Trypanosomiasis - Genetic stability seen in natural clones of Trypanosoma brucei

Vaccine Efficacy - Vaccination under suboptimal immune protection explored

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