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Anti-Infectives Week

Susan Hasty, Publisher

Table of Contents . . . November 1st, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Anti-Infectives Week | Other Publications

Antibiotic Resistance - Biotech company working to address problem of antibiotic resistance

Bacteriology - Triclosan's insertion in cell membrane may account for its antibacterial effect

Chronic Obstructive Pulmonary Disease - Increased IgE-antibodies to S. aureus enterotoxins studied in COPD patients

Colitis - Experimental colitis and the presence of bacteria studied in murine model

Listeriosis - New biosensor rapidly detects deadly food-borne pathogen

Acinetobacter Baumannii - Multiresistant Acinetobacter baumannii outbreak occurred in surgical room

Adenovirus - Membrane Cofactor Protein identified as adenovirus receptor

Anthrax - Prescriptions for antibiotics to prevent anthrax now uncommon

Anthrax - Researchers begin evaluating efficacy of JuvImmune immunostimulant platform

Antifungal Therapy - Oral fluconazole safe/effective empiric treatment for neutropenic fever

Antimicrobials - Elemental sulphur studied as an induced antifungal substance

Awards - Educators honored for linking hygiene and health

Bacterial Pathogen - Oligonucleotide array technology rapidly detects foodborne pathogenic bacteria

Bacteriology -  Enterococcus faecalis fsr two-component system controls biofilm development

Bacteriology - Biosynthesis study results of 55 bacterial strains reported

Bacteriology - Pharma company completes phase 1 clinical trial for complicated skin infections

Bacteriology - Significance of microbial interactions in biooxidation of pyrite

Biofilms -  Lactobacillus spp. biofilm growth promoted by Actinomyces spp., S. mutans

Bioterrorism - NIH grants awards for the development of human antibody against anthrax

Bovine Mastitis - Clinical bovine mastitis diagnosed in a Prototheca zopfii outbreak

Circovirus Type 2 - Porcine circovirus type 2 from pigs was in Croatia detected and characterized

Creutzfeldt-Jakob Disease - New York investigates rare brain-disease deaths in Ulster County

DNA Research - Viral DNA damage in presence of RB, UV light may make normal repair less likely

Dermatology - Pharma company acquires PURELL from GOJO industries

Diagnostic Devices - HIV diagnostic proves effective in Dominican Republic trials

Diagnostics - CGE-LIF cycling probe technology analyzes small samples for genomic DNA

Disease Prevention - In Zimbabwe, hair salons promote female condom use to protect against HIV

Disease Transmission - Study identifies target for preventing sexual transmission of HIV

Drug Delivery - Microencapsulation improves safety and efficacy of amphotericin B

Drug Development - Inhalation drug company secures new funding

Drug Development - Novel compounds exhibit antiviral and antitumor effects

Drug Development - Phase 1 clinical trial for intranasal delivery of antibiotic initiated

Emerging Pathogens - Emerging pathogen suggests amphibian trade should be closely monitored

Environmental Health - A new high-capacity biofilm reactor system studied for treating domestic sewage

Environmental Health - County officials in Oklahoma look for cause of infections

Epstein Barr Virus - EBV is integrated between REL and BCL-11A in American Burkitt lymphoma cell line

Finance - Company focused on antibiotic-resistant bacteria closes $1.1M investment round

Food-Borne Illness - Scientists have bionanotechnology recipe to find elusive bacteria

Fungal Infections - Aminocandin phase I trial initiated for systemic fungal infections

Global Health - GE launches healthcare and education initiative in Africa

Glycopeptide-Resistant Enterococci - Debate-guidelines for glycopeptide-resistant enterococci control have not worked

Group B Rotaviruses - Group B rotaviruses have been circulating in Western India since 1993

HIV/AIDS Epidemiology - HIV-1 non-B subtypes from heterosexual transmission predominate in Scotland

HIV/AIDS Research - APOBEC3G incorporated into HIV-1 virions through viral/nonviral RNA interactions

HIV/AIDS Research - Antisense U7 snRNAs and siRNAs targeting cyclophilin A inhibit HIV-1 replication

HIV/AIDS Research - Dying cells drive the capacity of HIV-1 to kill noncycling primary CD4+ cells

HIV/AIDS Research - HIV-1 infectivity enhanced by forming particle-mediated syncytia in CD4+ cells

HIV/AIDS Research - Host cell gene expression varies during HIV-1 latency or reactivation

HIV/AIDS Research - Memantine protects hippocampal neuronal function in HIV-1 encephalitis

HIV/AIDS Research - R5 HIV-1 replicates more efficiently in primary CD4+ cells than X4 HIV-1

HIV/AIDS Research - Structure of initiation complex of HIV-1 reverse transcription is not conserved

HIV/AIDS Research - TSG101 mutations that inhibit PTAP or VPS28 binding block HIV-1 budding

HIV/AIDS Research - Tumorigenesis by HHV-8 chemokine receptor vGPCR is accelerated by HIV-1 Tat

HIV/AIDS Therapy - CD4+ cell non-production during HAART due to inefficiencies at multiple steps

HIV/AIDS Therapy - Jury is still out regarding benefits of switching to protease-sparing regimen

HIV/AIDS-Related Pain Medicine - HIV-1 gp120-induced nitric oxide increases proinflammatory cytokines

Hepatitis C Virus Infection - Persistence of hepatitis C virus associated with human leukocyte antigen class 1

Infection Control - Disinfection, and sterilization adherence reduce hospital-related infections

Infectious Disease - Company awarded SIBR grant for infectious disease detection

Influenza - Bacterium causes U.S. flu vaccine shortage

Influenza - Study to test flu shot and nasal spray flu vaccine side by side

Influenza Vaccine - Vaccine failure underscores antiquated productions system

Influenza Virus - Antigenically and genetically similar influenza C viruses in Japan characterized

Influenza Virus - Influenza B virus lacks sequence homology to influenza A virus antigenic sites

International Collaborations - Scientists meet to work on strategy to fight global viruses

Legal Issues - Healthy monkey can be kept by owner

Legionnaires Disease - Officials probe Cherokee County outbreak of Legionnaire disease

Lentivirus - LEDGF/p75 is a component of functional lentiviral preintegration complexes

Leptospirosis - Unique Leptospira strain isolated from patient with pulmonary hemorrhage

Malaria - Two spermidine analogues show moderate in vitro inhibition, ineffective in vivo

Medical Devices - United Kingdom company begins research program on infection control

Meningitis Outbreak - Nosocomial meningitis outbreak caused by Acinetobacter baumannii

Meningococcal Disease - Domestic clones of N. meningitidis circulated in meningococcal disease outbreak

Mycobacterium Haemocanis -  M. haemocanis infection prevalence higher in kennel-raised than pet dogs

Nosocomial Infection - Catheter-related infections in European hospitals characterized

Otitis Media - Nasopharyngeal pathogens in Danish children with otitis media studied

Papillomatosis - Omomyc expression in the skin prevents Myc-induced papillomatosis

SARS - U.S. NIH grant awarded for development of nasally delivered SARS vaccine

SARS Coronavirus - Highly infectious SARS-CoV reveals cell tropism/receptor expression correlation

SARS Infection Control - Providing SARS infection control information to outpatients increases compliance

Salmonella Outbreak -  Salmonella outbreak traced to unshelled peanuts originating from one country

Squamous Cell Carcinoma - hCAP18(109-135) may be useful antitumor therapeutic agent for oral SCC

Stereoselective Oxidation - Active microorganism strains sought in secondary alcohols

Surgical Devices - Results of new heart surgery system discussed at conference

Swine Fever Virus - Optimized protocol developed for detection of classical swine fever virus

Tumorigenesis - IKK beta links inflammation and tumorigenesis in colitis-associated cancer

Usutu Virus - Pathology/viral distribution characterized in fatal usutu virus infection

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