Susan Hasty, Publisher
Table of Contents . . . February 7th, 2005
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Anti-Infectives Week | Other Publications
Anti-Infectives - Daptomycin is effective antibiotic against Gram-positive pathogens
Cystic Fibrosis - Azithromycin shows promising results in early clinical trials
Drug Development - Positive phase IIa data reported for Rambazole and Azoline in fungal infections
Food-Borne Disease - Polymyxin B attenuates Salmonella-induced endotoxin shock
HIV/AIDS Therapy - Dual CCR5/CXCR4 antagonist inhibits HIV-1 replication
Acinetobacter Baumannii - Multiresistant Acinetobacter baumannii clone identified in 24 hospitals
Adverse Drug Reaction - Interaction between valproic acid and carbapenems characterized
Anthrax - Anthrax toxin studied, acid-induced unfolding of domains revealed
Antimicrobials - Evolution of equine infection control programs reviewed
Antimicrobials - Food pathogens and food spoilage organisms inhibited by select raw honeys
Avian Influenza - Bird flu virus confirmed in chickens in Thailand
Biomedical Engineering - Mid-sized software system for lab testing launched by biotechnology company
Business Update - Healthcare consultancy releases analysis of European wound management market
Business Update - Infection control products producer awarded contract by Novation
Business Update - Pharmaceutical company completes level 1 American Depositary Receipts Program
Candida Infection - Very-low-birthweight infants may harbor Candida for a prolonged time period
Clinical Trails - Biopharma company reports encouraging Altastaph phase I/II results in adults
Clinical Trials - Aurexis phase II enrollment complete; Veronate phase III trial tracking well
Collaborations - Companies initiate partnerships to create enhanced monoclonal antibodies
Creutzfeldt-Jakob Disease - Sporadic Creutzfeldt-Jakob disease analyzed, role of plasminogen clarified
Diagnostics - FDA clearance granted for MRSA test
Diagnostics - PCR detects/monitors pathogenic viruses in immunosuppressed pediatric patients
Disease Prevention - Wash hands to help prevent colds and flu
Disease Threat - Boston University researchers did not report illness
Environmental Health - Scientists decipher genome of bacterium that cleans up groundwater pollutants
Epstein-Barr Virus - Epstein-Barr virus detected in lymphoma cells in mantle cell lymphoma patient
Epstein-Barr Virus - Lytic transactivator Rta induces Epstein-Barr virus latent membrane protein 1
Epstein-Barr Virus - Researchers' data advance epstein-barr virus research
Finance - Biotech company announces quarterly dividend for 6% convertible preferred stock
Finance - Company reports Q4 Cubicin revenues of $21.0M, year-end net revenue of $58.6M
Genotype - Clinical and nonclinical Acanthamoeba isolates studied, ATP hydrolysis revealed
HIV/AIDS Associated Disorder - IV immunoglobulin used to treat HIV patient with DILS-associated myositis
HIV/AIDS Drug Analysis - Interaction kinetic data improves HIV-1 protease inhibitor analysis
HIV/AIDS Pathogenesis - HIV nef limits virus-specific CD8 cellular host response
HIV/AIDS Pathogenesis - LEDGF/p75 contains a pair of evolutionarily conserved domains
HIV/AIDS Pathogenesis - Linear HIV viral DNAs containing an extra base are substrates for integration
HIV/AIDS Pathogenesis - Researchers detail new studies and findings in the area of HIV/AIDS pathogenesis
HIV/AIDS Pathogenesis - Target cell Cyclophilin A modulates HIV-1 infectivity
HIV/AIDS Policy - Corporate South Africa slow to response to HIV/AIDS crisis
HIV/AIDS Research - New data illuminates research in HIV/AIDS
HIV/AIDS Research - Recent findings illuminate research in HIV/AIDS
HIV/AIDS Research - Researchers provide details of new studies and findings in the area of HIV/AIDS
HIV/AIDS Research - Researchers report details of new studies and findings in the area of HIV/AIDS
HIV/AIDS Research - TGF-beta inhibits HIV-1 in mammary epithelial cells
HIV/AIDS Therapy - 400 mg indinavir may be efficacious and less toxic than ritonavir and efavirenz
HIV/AIDS Therapy - Amdoxovir + IMPDH inhibitors active against wild-type/drug-resistant HIV-1
HIV/AIDS Therapy - Arylsulfonamides inhibit wild-type and mutant HIV-1 protease
HIV/AIDS Therapy - High-throughput screening identifies NNRTIs with enhanced anti-HIV-1 activity
HIV/AIDS Therapy - Indinavir/ritonavir 667/100 mg toxicity profile may be similar to unboosted IDV
HIV/AIDS Therapy - N-substituted pyrrole derivatives block HIV fusion
HIV/AIDS Therapy - NRTIs cross the placenta by simple diffusion and concentrate in amniotic fluid
HIV/AIDS Therapy - Nucleoside analogues preserve M184V mutation in mixed dual infections
HIV/AIDS Therapy - Polyarginine inhibits gp160 processing by furin and suppresses HIV-1 infection
HIV/AIDS Therapy - Ritonavir has double-boosting function for both lopinavir and saquinavir
HIV/AIDS Therapy - Studies advance knowledge in HIV/AIDS therapy research
HIV/AIDS Therapy - d4T with/without 3TC is an alternative to ZDV for HIV-infected pregnant women
HIV/AIDS Treatment - HIV-focused biopharmaceutical company completes drug studies in Italy and Spain
HIV/AIDS-Associated Infection - Cryptococcal meningitis decreased/cerebral toxoplasmosis increased in HARRT era
HIV/AIDS-Related Drug Interaction - Nevirapine reduces racemic methadone/(R)-methadone levels in HIV infection
HIV/AIDS-Related Neuropathogenesis - Astrocyte dysfunction contributes to HIV Tat neurotoxicity
Health Promotion - Healthy Pride web site launched to address health issues in LBGT community
Helicobacter Pylori - H. pylori cag pathogenicity island disrupted in majority of patient isolates
Hepatitis C Virus - Hepatitis C is growing danger on Long Island, New York
Herpesvirus - HMGB1 facilitates RTA-mediated viral gene expression in gamma-2 herpesviruses
Herpesvirus - Murine gammaherpesvirus 68 glycoprotein B processing similar to KSHV gB & CMV gB
Immunodeficiency - Antibodies to Haemophilus and Streptococcus in IGIV products detected
Infections - Angiostrongylus cantonensis infection studied, specific signals identified
Infections - Rickettsia conorii infection studied, role of early signaling clarified
Influenza - RT-PCR using primers based on HA2 gene detects all 15 HA influenza A subtypes
Influenza Vaccine - Maine lifts restrictions on use of flu vaccine
Influenza Vaccine - Nearly 10,000 doses of flu vaccine available statewide in Arkansas
Influenza Vaccine - New Mexico lifts order restricting flu vaccine
Influenza Vaccine - Restriction on flu shots lifted in Oklahoma
Influenza Vaccine - Vaccine maker takes first steps toward vaccine against deadly flu strain
Listeria Monocytogenes - Mixed-genome DNA microarray identifies L. monocytogenes serotypes & subtypes
Lyme Disease - Borrelia burgdorferi studied, receptor on Ixodues scapularis revealed
Malaria - Novel malarial protease analyzed, computational predictions reported
Marine Parasite - Real-time PCR detects/quantifies Perkinsus marinus in environmental waters
Mergers & Acquisitions - Infection prevention and decontamination company completes acquisition of Cosmed
Methicillin-Resistant Staphylococcus Aureus - EMSRA strain tracked from one hospital as it spread to surrounding hospitals
Methicillin-Resistant Staphylococcus Aureus - Joint cooperation controls MRSA outbreak involving several hospitals
Mycobacterium Tuberculosis - Mycobacterium tuberculosis Cameroon family is molecularly characterized
Mycobactetium Brumae - Mycobactetium brumae caused catheter-related bloodstream infection
Nocardiosis - Nocardia nova caused sporotrichoid nocardiosis in HIV-infected patient
Norovirus - SDS/EDTA-pretreated chromatography paper strips used for Norovirus sampling
Papillomavirus - Nested PCR with PGMY09/11 and GP5+/6+ primer sets improves HPV DNA detection
Personnel - Anti-infective drug developer names chief medical officer
Pertussis Diagnosis - Cutoff points for antibody levels to pertussis toxin established
Philanthropy - Clinton Foundation and UNICEF launch tsunami water and sanitation fund
Philanthropy - Pharmaceutical company reports on its response to tsunami
Pneumocystis Carinii Therapy - Piperazine-linked bisbenzamidines active against Pneumocystis carinii
Pneumonia - Cytomegalovirus pneumonia not associated with bronchiolitis obliterans syndrome
Pseudomonas Aeruginosa - Carbapenem-resistant Pseudomonas aeruginosa outbreak strain produced VIM-8
SARS Outbreak - Strict infection control is an effective intervention following SARS exposure
Skeletal Tuberculosis - Skeletal tuberculosis may be suspect in cases of long-standing pain and swelling
Tuberculosis - Company announces breakthrough in treatment of TB and MDR-TB
Tuberculosis Therapy - Efficacy of culture media for levofloxacin susceptibility testing determined
Vibrio Parahaemolyticus - KP+/TDH+ environmental V. parahaemolyticus strains isolated
Water Contamination - Household storage practices increase water contamination in India
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