Anti-Infectives Week

Bacteriology - Some Staphylococcus aureus clones more virulent than others

HIV/AIDS Pathogenesis - Oligomerization required for HIV-1 Nef-induced Hck activation

HIV/AIDS Research - Cell lines with an integrated luciferase gene determine HIV-1 infectivity

Occupational Health - Programs to prevent needlestick injuries in healthcare workers launched

Staphylococcus Epidemiology - Methicillin-resistant Staphylococcus in Hong Kong reported

Antibiotics - R-baclofen in pharmaceutical formulations determined

Antiviral Therapy - Topical gel inhibits HIV and HSV infection in cervicovaginal lavage fluid

Asthma - Phase 1 study of inhaled asthma product initiated

Atherosclerosis - Studies add new findings to atherosclerosis body of knowledge

Bacteriology - Novel microarray enables direct detection of S. aureus mRNA

Bifidobacterium Bifidum - Monomeric aspartate racemase Bifidobacterium bifidum molecularly analyzed

Botulinum Toxin - Botulinum toxin therapy studied, antibody-induced failure reported

Business Update - New filter protects from exposure to waterborne contaminated equipment

Coccidian Parasite -  C. cayetanensis important parasite in immunocompromised persons

Diagnostics - Assays used to identify potential treatments for drug-resistant strain of HIV

Diagnostics - Elispot assay optimized to detect cytomegalovirus-specific CD8+ T lymphocytes

Diagnostics - Latex agglutination test diagnoses visceral leishmaniasis in HIV co-infection

Diagnostics - Subcutaneous dirofilariasis case caused by Dirofilaria repens

Disease Transmission - Safer mother-to-child anti-HIV drugs effective, but more expensive

Drug Development - Development initiated for a new class of antibiotics for super bugs

Drug Development - Generic drug company announces tentative FDA approval for anitbacterial drug

Drug Development - Thiocyanato complexes have cytotoxic and antimicrobial properties

Drug Resistance -  Helicobacter pylori studied, bacillary to coccoid conversion clarified

Endotoxic shock - Antibacterial peptide PR-39 studied, benefits in endotoxic shock shown

Enterococcus Faecalis - Gentamicin-resistant Enterococcus faecalis strains characterized

Epidemiology - Water is a major vehicle for Cryptosporidium transmission

Epidemiology - Waterborne transmissions increasing for Toxoplasma gondi

Fibronectin - Role of Streptococcus pyogenes F1 in fibronectin conformation clarified

Giardia & Cryptosporidium Infections - Nordic countries incidence estimated for Giardia & Cryptosporidium

HIV/AIDS Diagnostics - Neurospychiatric symptoms from efavirenz difficult to diagnose in HIV infection

HIV/AIDS Diagnostics - Rapid and standard HIV Ab ELISAs negatively affected by HIV-indeterminates

HIV/AIDS Disease Progression - Anti-NTM antibodies is a useful prognostic marker for HIV disease

HIV/AIDS Drug Resistance - Certain HIV-1 resistance-associated mutations are highly stable

HIV/AIDS Drug Resistance - NRTIs may have continued anti-HIV-1 activity despite presence of resistance

HIV/AIDS Epidemiology - HIV-1 genetically diverse in rural eastern Cameroon

HIV/AIDS Epidemiology - Homeless in San Francisco HIV seroconversion incidence/risk factors estimated

HIV/AIDS Pathogenesis - CD27 expression promotes long-term survival of CD8+ cells in HIV-infection

HIV/AIDS Pathogenesis - HIV-1 Nef does not significantly affect viral infectivity in target cells

HIV/AIDS Pathogenesis - HIV-1 Nef promotes physical interaction between endogenous AP-1 and MHC-I

HIV/AIDS Pathogenesis - Perlecan mediates cellular uptake of HIV-1 Tat

HIV/AIDS Pathogenesis - Research add new data to HIV/AIDS pathogenesis body of knowledge