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Anti-Infectives Week

Susan Hasty, Publisher

Table of Contents . . . June 13th, 2005

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Anti-Infectives Week | Other Publications

Anti-infectives - Biodegradable antibiotic-releasing catheter polymer developed

Antimicrobial Resistance - Ciprofloxacin-resistant Pseudomonas aeruginosa investigated

Bloodstream Infection - Categorization and blood culture Gram stains can guide early treatment

HIV/AIDS Therapy - HIV reverse transcriptase mutations confer drug resistance

Wound Care - U.S. FDA grants clearance for absorbant antimicrobial barrier dressing

Adenovirus - Adenovirus protein 100k examined, translational regulation elucidated

Antibiotic Resistance - Pathogens can have a strong effect on host behavior

Apoptosis -  Salmonella enterica analyzed, apoptosis-like macrophage death caused

Avian Influenza - Alferon LDO in trials as experimental antiviral therapy

Bacteriology - Biacticap is the latest weapon in the fight against MRSA

Bacteriology - Recent findings in bacteriology described

Business & Finance - Biopharmaceutical firm reports loss of $0.40 per share, provides clinical update

Business & Finance - Company focused on lipids-associated diseases reports Q1 2005 results

Business & finance - Biology corporation retains Macias Gini & company LLP as independent auditors

Business Update - Biopharmaceutical firm establishes Canadian operations

Business Update - Book takes on questions facing today's healthcare industry

Collaborations - Companies sign letter of intent to collaborate in marketing, vaccine supply

Collaborations - Joint development program formed with the U.S. Army

Disease Associations -  Porphyromonas gingivalis fimbriae examined, inhibitory effects revealed

Disease Outbreaks - Vaccine shortages reflect problems in pharmaceutical industry, doctor says

Drug Allergy - In vitro test facilitates diagnosis of delayed hypersensitivity reactions

Drug Development - Antifungal agent Mycamine available to physicians

Drug Development - Antifungal agent derived from Streptomyces albidoflavus PU 23

Drug Development - Data presented from phase III miconazole Lauriad Bioadhesive study

Encephalopathy - Pathogenesis of influenza-associated encephalopathy determined

Epstein-Barr Virus - Epstein-Barr virus examined, shedding by astronauts chronicled

Finance - Biopharmaceutical company announces third quarter fiscal 2005 financial results

Finance - HIV test maker reports Q1 revenues of $731,885

Finance - Pathogen-inactivation company applies for Amex listing

Finance - Vitex Files Shelf Registration Statement

Gastric Cancer - Cancer statistics in Japan 2003 summarized

Genetics & Genomics - Gene expression studied to determine causes of tumor progression

Gingivitis - Novel chlorhexidine formulation has reduced side effects

HIV/AIDS Diagnostics - Dried blood spots improve access to HIV diagnosis in infants

HIV/AIDS Diagnostics - One-step nested PCR monitors HIV replication

HIV/AIDS Diagnostics - Rapid HIV testing has reduced test results from days to minutes

HIV/AIDS Drug Development - Developed HIV-1 protease inhibitors active against multidrug-resistant virus

HIV/AIDS Drug Development - Developed tricyclic phtalimide analogues inhibit HIV-1 integrase

HIV/AIDS Drug Development - Low molecular weight HIV-1 protease dimerization inhibitors developed

HIV/AIDS Drug Development - Lysozyme nonapeptide HL9 has anti-HIV activity

HIV/AIDS Drug Development - Method predicts structure-based activity of HIV-1 RT inhibitors

HIV/AIDS Drug Resistance - Antiretroviral resistance not a major determinant of disease progression/death

HIV/AIDS Epidemiology - HIV infection rate not significantly changed among adolescents in South Africa

HIV/AIDS Epidemiology - Multiple partners and unprotected sex fuel HIV/AIDS epidemic in Africa

HIV/AIDS HAART - Adverse experiences increased following quadruple-drug induction HAART

HIV/AIDS Nutrition - Fruit/vegetable increase improves oxidative stress indicators in HIV/AIDS

HIV/AIDS Pathogenesis - CD4 engagement-induced cell surface rearrangement facilitates HIV entry

HIV/AIDS Pathogenesis - CD81 increases HIV-1 gene expression in CD4 cells via transcription factors

HIV/AIDS Pathogenesis - HIV Gag concentrates in specific plasma membrane areas rapidly after translation

HIV/AIDS Pathogenesis - HIV-1 gp120 regulates cxcr4-mediated signaling in neural progenitor cells

HIV/AIDS Pathogenesis - HIV-1-induced macrophage gene expression includes the p21 gene

HIV/AIDS Pathogenesis - JM4 is a four-transmembrane protein binding to CCR5 receptor

HIV/AIDS Pathogenesis - Kinetic factors control HIV-1 cell entry efficiency/entry inhibitor efficacy

HIV/AIDS Pathogenesis - Rad3-related protein and GADD45 alpha mediate HIV-1 Vpr-induced apoptosis

HIV/AIDS Pathogenesis - TFII-I regulates induction of HIV-1 LTR in cooperation with USF

HIV/AIDS Pathogenesis - TNF-alpha stimulates HIV-1 production in adipocytes

HIV/AIDS Prevention - Most rural health institutions in Ethiopia report reusing needles/syringes

HIV/AIDS Research - Inverse relationship between heparin binding by HIV gp120 and its thiol content

HIV/AIDS Therapy - U.S. FDA grants traditional approval status to 3-medication tablet for HIV

HIV/AIDS Vaccines - Research in HIV/AIDS vaccines provides new insights

HIV/AIDS Vaccines - U.N. report on combating AIDS in developing countries recently released

HIV/AIDS-Related Disorder - HIV-related pulmonary hypertension does not worsen with HAART interruption

HIV/AIDS-Related Infection -  Acinetobacter baumannii folliculitis detected in patient with AIDS

HIV/AIDS-Related Infection -  Mycobacterium peregrinum infection identified in AIDS patient

HIV/AIDS-Related Infection - Rarely diagnosed cardiac aspergillosis is fatal in HIV-infected patients

Hepatitis B Virus - U.S. FDA approves Pegasys for the treatment of chronic hepatitis B

Hepatitis C - Study examines two approaches for liver disease treatment

Human Papillomavirus - Papillomavirus studied, protein-mediated endosomal pH alteration revealed

Infectious Disease Research - NIAID-supported research combats/elucidates emerging infectious diseases

Kaposi Sarcoma-Associated Herpesvirus - Recent findings in kaposi sarcoma-associated herpesvirus described

Leukemia - Survival of a child with ALL and Scedosporium prolificans infection examined

Lung Cancer -  M. tuberculosis infection associated with FHIT gene LOH in lung cancer

Malaria - Reports describe recent advances in malaria research

Malaria Therapy - Azithromycin and chloroquine effective in combination

Meningitis - Distinct lineage of echovirus 30 probable cause of aseptic meningitis outbreak

Mergers & Acquisitions - Respiratory-focused healthcare company to acquire Pulmonetic Systems, Inc.

Methicillin-Resistant Staphylococcus Aureus - Soap-sharing/pre-existing cuts caused recurring MRSA infections in football team

Mycobacterium Smegmatis -  M. smegmatis mutants unable to grow at low pH in the presence of CCCP

Mycobacterium Smegmatis -  M. smegmatis re1A homolog affects cell appearance/viability/gene expression

Mycobacterium Tuberculosis - MTB mycolic acid elicits pathogen-associated host innate immune responses

Norovirus - Factors identified with bovine norovirus seropositivity in veterinarians

Norovirus Outbreaks - GII/5 was dominant genotype in norovirus outbreak in Japan

Nosocomial Infections - National medical agency grants special compassionate use for diarrhea therapy

Nucleopolyhedrovirus - Nucleopolyhedrovirus epizootics initiate decline of N. abietis populations

Personnel - Biology corporation appoints Ulrich M. Grau, PhD, to board of directors

Pharmaceutical Research - Data about wound healing presented at annual meeting

Prions - Prion transmission analyzed, cross-species conformation revealed

Rabies - Stochastic special model predicts spatial dynamics for raccoon rabies emergence

Retroviruses - TRIM5 alpha proteins block retrovirus infections across primate species

SARS Coronavirus - Anti-SARS-coronavirus activity of cepharanthine determined

Simian Immunodeficiency Virus - Active SIV CNS infection correlates with neurological disease

Staphylococcus Aureus -  Staphylococcus aureus analyzed, proteome analysis reported

Staphylococcus Aureus -  Staphylococcus aureus studied, endocarditis role for teichoic acid revealed

Tuberculosis - Ipr1 gene mediates innate immunity to tuberculosis

Tuberculosis - Multiple factors influence inability to control tuberculosis in China

Tuberculosis - PI3P retention different in phagosomes containing live or dead mycobacteria

Tuberculosis - Tuberculosis decline in Netherlands over the past decade result of cohort effect

Tuberculosis Drug Development - Quinoxaline-2-carboxylate 1,4-dioxide derivatives have anti-MTB activity

Vaccine Development - Biopharma company begins studies of vaccine to produce antistaph antibodies

Yersinia Pestis -  Y. pestis CRISPR elements acquire new repeats by bacteriophage DNA uptake

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