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Hepatitis C Virus

Shorter course of combination therapy approved in E.U. for some hepatitis C patients

Published in Anti-Infectives Week, October 31st, 2005

Schering-Plough Corporation (SGP) announced that the European Commission has approved revised dosing instructions allowing for a shorter, 24-week course of Peg-Intron (1.5 mcg/kg once weekly) and Rebetol (800-1,200 mg daily) combination therapy.

The revised dosing instructions are for use among a subgroup of patients with chronic hepatitis C virus (HCV) genotype 1 infection and low viral load (less than 600,000 IU/ml) who have achieved rapid virologic response, defined as undetectable virus (HCV-RNA negative) at week 4 of treatment that is maintained through week 24. The approval follows a positive opinion granted on July 28, 2005, by the Committee for Medicinal...

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