Anti-Infectives Week
Susan Hasty, Publisher
Table of Contents . . . December 5th, 2005
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Anti-Infectives Week | Other Publications
Anti-Infectives - Daptomycin, linezolid, and quinupristin/dalfopristin used to manage infections
Antimicrobial Resistance - Mechanism of fluoroquinolone resistance development and spread are examined
Antimicrobial Resistance - MutS fusion proteins as recognition elements of DNA chips detect DNA mutations
Antimicrobials - Xanthohumol is a broad-spectrum anti-infective agent
Malaria - Scientists find more evidence of resistance to once effective malaria drugs
Adverse Drug Reaction - Adverse events similar between levofloxacin and conventional first-line regimens for active TB
Anti-Infectives - Dutch biotech teams up with ACE BioSciences and Harvard to accelerate bacterial antibody program
Anti-Infectives - U.S. FDA recognizes alcohol-based hand sanitizers as safe and effective for consumer use
Antibiotic Resistance - Antimicrobial resistance is common in Shiga toxin-producing E. coli
Antifungals - Oral posaconazole has clinical activity against CNS fungal infections
Antimicrobials - Recent findings illuminate research in antimicrobials
Auricular Chondritis - Ear piercing associated with auricular chondritis outbreak
Avian Influenza - Ampligen-Relenza is synergystic combination against avian flu virus, study shows
Avian Influenza - Diagnostics company launches test kit for influenza and avian flu virus
Avian Influenza - Economic cost to hospitals from an avian flu pandemic could be huge, researcher says
Avian Influenza - South Dakota university will soon be H5N1 testing center
Awards - New biotech company developing antibacterial compounds wins Bionow award
Bacteriology - Horizontal gene transfer helps bacteria gain new abilities in response to a changing environment
Bacteriology - Studies describe new findings in bacteriology research
Chronic Otitis Media - Canal wall reconstruction tympanomastoidectomy with mastoid obliteration effective for cholesteatoma
Collaborations - Akorn signs deal with India-based firm to develop and supply an oral anti-infective drug product
Collaborations - Infectious disease-focused company enters alliance to discover antibody therapies for pneumonia
Complementary & Alternative Medicine - Hyperlactatemia and lactic acidosis successfully treated in HIV patients taking NRTIs
Complementary & Alternative Medicine - Palm vitamin E is more potent than alpha-tocopherol in improving dermal wound healing
Dermatology - New therapies, procedures in treatment of acne discussed at dermatology meeting
Diabetes Complications - Anti-infective therapy for foot ulcers in patients with diabetes requires special care
Diagnostics - Asymptomatic bacteriuria is predictor of increased urosepsis risk in diabetics
Diagnostics - Pathogenic Ochrobactrum have distinctive phenotypes, detectable with API 20NE
Diagnostics - Researchers provide details of new studies and findings in the area of diagnostics
Disease Transmission - New study finds malaria could play key role in mother-to-child transmission of HIV
Drug Development - Amoxicillin Pulsys phase III trial set to begin following meeting with U.S. FDA
Drug Therapy - Trimethoprim-sulfamethoxazole with doxycycline superior to standard 4-drug maintenance regimen
Environmental Health - Reports published on the growing health effects of global warming
Finance - California biotech company announces $12 million private placement
Finance - Developer of pathogen inactivation process completes $12 million private placement
Finance - Pharmaceutical company reports Q3 revenues up 23%, product sales up 21%
Fungal Infection - Candidemia adds to burden of excess mortality, hospital stay, and cost
Genetics & Genomics - C. neoformans used as molecular fungal pathogenesis model to identify drug targets
Genetics & Genomics - Drug-resistant HIV-1 mutations in the former Soviet Union are identified
Genetics & Genomics - Suppression subtractive hybridization identifies different regions among Yersinia pestis strains
Grant Funding - Gates Foundation grant awarded to develop immune system test for HIV/AIDS patients
HIV/AIDS Diagnostics - Rapid HIV tests more cost effective than ELISAs in low-risk populations
HIV/AIDS Drug Development - HIV-1-PR inhibitors are identified that do not create resistance
HIV/AIDS Drug Resistance - Some HIV-1 HRI sequence variations affect sensitivity to T-20 but not T-1249 fusion inhibitors
HIV/AIDS Drug Resistance - U.K. scientists concerned over country's high HIV-drug resistance rates
HIV/AIDS HAART - Activated monocytes are enriched in cerebrospinal fluid of patients receiving HAART
HIV/AIDS HAART - Studies describe new findings in HIV/AIDS HAART research
HIV/AIDS Pathogenesis - CXCR4 TM mutations decrease HIV-1-mediated cell fusion but not binding activity of SDF-1alpha
HIV/AIDS Pathogenesis - New findings in the area of HIV/AIDS pathogenesis detailed
HIV/AIDS Therapy - E.U. commission approves Aptivus for the treatment of HIV
HIV/AIDS Therapy - Reports add new data to HIV/AIDS therapy research
HIV/AIDS Therapy - Therapeutic education program increases HAART compliance
HIV/AIDS Transmission - Chorioamnionitis is associated with placental transmission of HIV-1 subtype E
HIV/AIDS Vaccine - De novo responses against escape variants of CD8 cell epitopes are generated in HIV-1 infection
HIV/AIDS Vertical Transmission - Zidovudine crosses the placenta in the first trimester of pregnancy
HIV/AIDS-Associated Lipoatrophy - HIV-positive men with or without lipoatrophy have less subcutaneous adipose tissue
Hematology - Disease management company contributes to first sepsis biomarker conference
Hepatitis B Therapy - Interferon/long-term lamivudine combination therapy is effective in hepatitis B
Hepatitis B Virus - Entecavir is well tolerated in lamivudine-refractory hepatitis B patients
Hepatitis B Virus - Hepatitis B e antigen-negative infection is prevalent in West Bengal, India
Hepatitis Therapy - Zinc supplementation may provide complementary therapy of chronic hepatitis C
Histoplasma Vaccine - Apoptosis modulates protective immunity to Histoplasma capsulatum
Infectious Diseases - Alveolar macrophage response to P. aeruginosa and B. cepacia is similar
Infectious Diseases - Dengue fever-carrying mosquitoes are found in Holland
Infectious Diseases - Genetic sequencing uncovers new bacterial species associated with vaginosis
Infectious Diseases - Leptin enhances TNF-alpha production in LPS-stimulated Kupffer cells
Kawasaki Disease - Researchers zero in on the possible cause of Kawasaki disease
Lymphatic Filariasis - Pharmaceutical company focuses on neglected disease with new manufacturing investment in Africa
Malaria Therapy - P. falciparum gene contains sequences that are potential malaria targets
Malaria Therapy - Intermittent malaria therapy can reduce malaria and anemia in infants
Malaria Vaccine - Follow-up study shows malaria vaccine effective over 18-month observation period
Melanoma - Combined effects evident in melanoma drug resistance
Mergers & Acquisitions - Majority holding in anti-infectives research acquired by Santo Holding AG
Mycobacteria Vaccine - Cellular immune responses to Mycobacterium avium paratuberculosis antigens characterized
Natural Products - Many naturally derived anti-HIV agents have other medicinal values
Natural Products - Mexican medicinal plants have antimycobacterial activity
Nosocomial Infections - Community-acquired MRSA strains have not been established in hospitals in Western Australia
Nosocomial Infections - Patients with invasive disease are at greater risk of acquiring healthcare-associated MRSA
Nosocomial Infections - Research to identify best ways of treating and preventing hospital superbugs
Otitis Media Therapy - Updated clinical practice guidelines for acute otitis media are released
Pathogens - Brassicaceae AvrBs3-like effectors are involved in virulence
Personnel - Biopharma company names Gorbach chief medical officer, Sr. VP medical affairs
Pharmaceutical Research - Moxifloxacin has variable pharmacodynamics against anaerobic and aerobic pathogens
Pharmaceutical Research - Single 2 g dose of azithromycin microspheres as effective as 7-day levofloxacin course
Pharmaceutical Research - Tigecycline has favorable pharmacokinetic profile in early animal studies
Pneumococcal Disease - Prevalence of pediatric pneumococcal serotypes is increased in elderly
Preventive Medicine - Screening high TB-prevalent immigrants by chest X-ray allows for early detection and treatment
Quality Assurance - False positive S. zooepidemicus resistance related to inadequate quality control
Shigellosis Vaccine - Drug resistance prompts need for shigellosis vaccine in Thailand
Staphylococcus Aureus - Community-associated methicillin-resistant Staphylococcus aureus is on the rise
Surgical Technology - Balloon dacryocystoplasty safe and effective for pediatric patients
Surgical Technology - Repeated laparotomies don't affect early healing of experimental intestinal anastomoses
Transplant Medicine - Acyclovir therapy does not prevent recurrent post-transplantation hepatitis
Typhoid Fever - Drug resistance increases need for typhoid and paratyphoid fever vaccines
Virology - Human osteosarcoma cell line expresses herpes simplex type-l thymidine kinase
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