Anti-Infectives Week
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Anti-Infectives Week
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Aspergillosis
Abelcet prolongs survival and reduces organ fungal load in CNS aspergillosis
December 12th, 2005
Abelcet significantly prolongs survival and reduced organ fungal load in central nervous system aspergillosis. "Currently, few options exist to treat central nervous system (CNS) aspergillosis, which is usually fatal. We tested the efficacy of Abelcet and caspofungin, alone and in combination for treatment of this disease. Male CD-1 mice were immunosuppressed with 200 mg/kg cyclophosphamide 2 days prior to infection and every 5 days thereafter," investigators in the United States report. "In the first study, mice were infected intracerebrally with 2.1x106 conidia/mouse of Aspergillus fumigatus; 10 days of once daily therapy began...
Source: Anti-Infectives Week (2005-12-12)
|
