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Anti-Infectives Week

Susan Hasty, Publisher

Table of Contents . . . December 26th, 2005

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Anti-Infectives Week | Other Publications

Adverse Drug Reaction - Bacitracin-induced anaphylaxis during pacemaker surgery reported

Drug Resistance - SHV-type ESBLs confer cefepime resistance in one-third of Enterobacter cloacae isolates

Medical Devices - DialGuard with ClarEtox efficiently removes bacterial contamination from water and dialysate

Periodontal Disease - Hydroxyl radicals play key role in phototoxic effects of blue light on periopathogens

Virology - Antiviral-resistant influenza viruses were susceptible to novel neuraminidase inhibitors

Antibacterial Agents - Drug maker introduces the first unit-of-use delivery system for Mupirocin Ointment USP 2%

Antibiotics - Cubicin maker selects ACS Dobfar as single-source API supplier

Arthritis - Review discusses benefits of health education in osteoarthritis care

Avian Influenza - A 2002 disease threat offers lessons for avian flu preparedness

Avian Influenza - The threat of avian influenza pandemic grows, but precautions can be taken

Bacteriology - Factors affecting staphylococcal recovery following peritonitis in CAPD were studied

Bacteriology - KP infection decreased blood TNF-alpha and increased blood IL-1 beta levels in DM mice

Bacteriology - Neostigmine is not protective against histopathologic organ injury in murine endotoxemia

Bacteriology - RF power has potential as an alternative to disinfect farm wastewater before recycling

Bacteriology - Reports describe recent advances in bacteriology research

Bioterrorism - Researchers develop a possible broad-spectrum defense against germ warfare

Blood Exposure - Human bites and blood exposures in New York City schools have potential for serious outcomes

Business & Finance - Maker of bacteria-inhibiting products announces planned corporate restructuring

Cardiology - Updated infection-control guidelines focus on patients and personnel in the cardiovascular cath lab

Cholera - Human infection with cholera causes bacteria to become more infectious

Clinical Trials - Once weekly dalbavancin as effective as twice daily linezolid for complicated SSSIs

Collaborations - Australia-based Institute for Eye Research to test selenium coated contact lenses

Diabetes Complications - V.A.C. Therapy shown effective and safe for healing diabetic foot amputation wounds

Diagnostics - RIDASCREEN EIA is sensitive but not specific for the detection of norovirus outbreak specimens

Diagnostics - Real-time PCR improves diagnostic yield, but raises treatment costs

Disease Trends - Are U.S. flu death figures more public relations than science?

Drug Delivery - Microparticle-based lung delivery of isoniazid decreases isoniazid metabolism

Drug Development - Antibiotic inhibits siderophore biosynthesis in M. tuberculosis and Y. pestis

Drug Development - ERK protein activation assists in adipocyte maturation and regulation of lipid blood level

Drug Development - Novel benzoxazole derivatives synthesized as anticancer, anti-HIV-1, and antimicrobial agents

Endocarditis - U.S. FDA accepts Cubicin sNDA and grants priority review

Epidemiology - IgG diphtheria antitoxin levels inadequate among blood donors in Rio de Janeiro

Epidemiology - Pediatric tuberculosis surged in non-European and immigrant populations in New Zealand

Escherichia Coli -  E. coli producing CTX-M-type beta-lactamases are more likely to cause repeat UTIs

Food Safety - Food sanitation, consumer information plan launched to prevent food-borne illnesses

Gene Therapy - Hepatocellular carcinoma xenografts are eradicated by inducible gene therapy

Genetics & Genomics - Gene expression varies in the Bdellovibrio predatory life cycle

Gonorrhea - MacA-MacB efflux system in Neisseria gonorrhoeae is characterized

HIV/AIDS Diagnostics - Bayer TruGene genotype assay detects and characterizes non-subtype-B HIV-1 strains

HIV/AIDS Diagnostics - Researchers' findings advance HIV/AIDS diagnostics research

HIV/AIDS Drug Development - Beta-chemokine analogues inhibit HIV-1 in mononuclear cells from HIV/TB coinfected patients

HIV/AIDS Drug Development - Surfactant protein D binds to HIV gp120 and inhibits viral replication

HIV/AIDS Drug Development - Vaginally delivered SIV-cell fusion inhibitors protect macaques from SHIV infection

HIV/AIDS Drug Pharmacokinetics - Pharmacokinetics of antivirals varies during the first weeks of life

HIV/AIDS Drug Resistance - Tipranavir resistance phenotype associated with complex genotypic changes in HIV protease

HIV/AIDS HAART - Amdoxovir is well tolerated and reduces HIV viral load

HIV/AIDS HAART - HAART interruptions do not restore antiviral efficacy in pre-treated patients with drug failures

HIV/AIDS HAART - Stavudine dose reductions may ameliorate complications without compromising antiviral activity

HIV/AIDS Healthcare Services - Holistic Native Network integrates HIV/AIDS, substance abuse, and mental health services

HIV/AIDS Microbicide - Anti-HIV vaginal microbicide has no adverse effects on vaginal pH

HIV/AIDS Pathogenesis - Complex determinants in HIV-1 gp120 mediate CXCR4-dependent infection of macrophages

HIV/AIDS Pathogenesis - Cytotoxic T lymphocytes can kill 0.7 to 3 HIV-infected target cells per day

HIV/AIDS Pathogenesis - HIV-1 Vpr interacts with antiapoptotic mitochondrial protein HAX-1

HIV/AIDS Prevention - Drug company support is critical to advancing AIDS prevention effort, says Zeda Rosenberg

HIV/AIDS Prevention - Financial incentives increase attendance at workshops for at-risk urban populations

HIV/AIDS Therapy - UCLA findings show that the immune response to HIV differs, even in identical twins

HIV/AIDS Vaccine - HIV-1 p24 may persist during long-term HAART

HIV/AIDS Vaccines - Studies advance knowledge in HIV/AIDS vaccines research

HIV/Tuberculosis Coinfection - Coinfected children not taking HAART have poor outcomes on anti-TB therapy

HIV/Tuberculosis Transmission - Family caregivers in Thailand put themselves at risk for HIV/TB transmission

Haemophilus Influenzae -  H. influenzae capsule deficient serotype can establish an invasive infection

Helicobacter Pylori -  Helicobacter pylori infection alters gastric epithelial cell gene expression

Helicobacter Pylori - Studies describe new findings in helicobacter pylori research

Hepatitis B Therapy - Genomic analysis conducted of anti-hepatitis B virus activity

Hepatitis C Therapy - Interferon-ribavirin therapy does not affect bone density in chronic hepatitis C

Herpesvirus Infection - Valacyclovir reduces the duration of herpes gladiatorum infection

Hospitalization Trends - Hospital admissions for HIV are down by half since 1995, according to U.S. government statistics

Immunology - Immunostimulation alone is insufficient to enhance antiviral T-cell reactivity

Immunology - Researchers link NPY hormone with immune system function

Infectious Diseases - Amphora selected for microbicide clinical trial

Infectious Diseases - Medical soldiers protect world borders from infectious diseases

Intra-Abdominal Infections - U.S. FDA approves new indication for Avelox (moxifloxacin HCl)

Klebsiella Pneumoniae - Multiresistant K. pneumoniae outbreak associated with contaminated roll boards in ORs

Malaria - Researchers' work adds to malaria body of knowledge

Malaria - Trimethoprim-sulfamethoxazole prevents falciparum malaria infection

Medical Devices - Positive results reported from in vivo study of urinary catheter anti-infective coating

Medical Devices - Russian-based companies sign agreement to ensure cobalt-60 for healthcare industry

Obesity Complications - Bariatric surgery does not add risk of postoperative wound infection in morbidly obese

Ophthalmology - International Trachoma Initiative joins forces to eliminate trachoma in Ethiopia

Parasitology - Trichinellosis shows a benign course and a milder clinical picture in children than in adults

Parasitology - Vitamin B5 analog inhibits P. falciparum pantothenate kinase and malaria proliferation

Pediatric Malaria Therapy - Methylene blue plus chloroquine safe for young African children, but has limited efficacy

Pediatric Neuropsychiatry - Lorazepam and plasmapheresis can improve symptoms in patients with catatonia

Pneumonia - Pneumonia hospitalization rates are on the rise for older adults

Product Distribution - Madaus, Srl, enters into agreement for ProQuin XR in Europe

Salmonellosis -  Salmonella stress management is related to behavior during intestinal colonization

Smallpox - Serious adverse reactions to smallpox vaccine appear to be limited

Stem Cell Transplantation - Almost half of HSCT patients with high-grade CMV antigenemia develop CMV disease

Stem Cell Transplantation - Virus-induced hemorrhagic cystitis is a frequent complication after AHSCT

Surgical Technology - Moxifloxacin 0.5% ophthalmic solution has higher antibiotic activity than gatifloxacin 0.3%

Surgical Technology - Retroperitoneoscopic renal pedicle lymphatic disconnection superior to open surgery

Tuberculosis - Study suggests that anticancer chemotherapy is not an obstacle in treating tuberculosis

Vaccines - Phase I trial of C. difficile vaccine in elderly subjects begins

Virology - Performing monkeys in Asia carry viruses that could jump species to humans

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