Anti-Infectives Week
Susan Hasty, Publisher
Table of Contents . . . January 30th, 2006
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Anti-Infectives Week | Other Publications
Amoxicillin - Amoxicillin/clavulanic acid eradicates pathogens from the nasopharynx in acute sinusitis
Antibacterial Agents - Ceftriaxone should be considered for surgical prophylaxis
Drug Development - Type IV pili-binding peptide R inhibits Salmonella Typhi infection
Food Safety - B. cereus biofilm exposed to air at high relative humidity promotes spore production
Infectious Diseases - Partnerships among government, academia, and industry needed to combat infectious diseases
Antibacterial Agents - Oral isotretinoin effectively reduced antibiotic-resistant propionibacteria
Antibiotics - SXN motif of PBP 5 appears intimately involved in catalytic mechanism of deacylation
Antimycobacterial Activity - 5-Substituted pyrimidine nucleosides active against Mycobacterium avium
Avian Influenza - Safety engineers offer influenza infection control tips
Bacteriology - Findings describe new data in bacteriology research
Blood Safety - Pharma company submits CE Mark application for Intercept Blood System for plasma in Europe
Burn Care - EGF appears to enhance dermal matrix formation and improve wound mechanical strength
Business & Finance - Junovan maker completes sale of noncore assets to Pharmexa, A/S, for $12M
Cervical Screening - Racial differences exist in attitudes towards cervical screening in HIV-positive women
Chronic Hepatitis C - Findings advance knowledge in chronic hepatitis C research
Clinical Trials - Durable efficacy of enfuvirtide plus optimized background of retrovirals demonstrated over 48 weeks
Clinical Trials - Initial subjects enrolled, dosed in trials of antibiotic for gastrointestinal illnesses
Clinical Trials - Studies show investigational antibiotic for skin infection similar to standard therapy
Disease Control - Malaria mosquito eradicated in KwaZulu-Natal after reintroduction of DDT
Drug Delivery - Modified caspofungin solution suitable for aerosolization
Drug Delivery - Spray-freeze-dried liposomal ciprofloxacin powder developed for inhaled aerosol delivery
Drug Development - Indirubin-3'-monoxime inhibits P-TEFb function and HIV-1 replication
Drug Development - New formulation of Leukine with extended shelf life launched
Drug Resistance - Drug resistant Plasmodium falciparum mutations prevalent during malaria epidemic
Drug Resistance - MDR TB detected in previously untreated and previously treated cases in Galicia
Drug Resistance - Multidrug resistant strains of nontyphoid Salmonella increasing in Israel
Drug Resistance - Trypanosma resistance to berenil is associated with upregulation of TeDR40
Drug Safety - LPV/RTV further increases total and HDL cholesterol without affecting total/HDL ratio
Efavirenz - Efavirenz treatment causes neurological symptoms distinct from depression and anxiety
Epidemiology - Population density important in the spread of SARS
Filariasis - Ivermectin and diethylcarbamazine had positive, but varied, effects in filiariasis treatment
Finance - Female health products company reports Q4 2005 net revenues up 90% over year ago
Finance - Novogen’s U.S. subsidiary postpones initial public offering
Fungal Infections - Ingestible antimicrobial formula kills Candida species
HIV/AIDS Adverse Drug Reaction - HIV entry inhibitor TAK-779 attenuates atherogenesis in LDL receptor deficiency
HIV/AIDS Antimicrobials - Mannose-binding lectin modulates cytokine response and HIV replication
HIV/AIDS Behavioral Medicine - High-risk sex with uninfected partners prevalent in patients with drug-resistant viremia
HIV/AIDS Drug Delivery - Subcutaneous IL-2 positively impacts long-term quality of life in HIV/AIDS
HIV/AIDS Drug Delivery - Zidovudine plasma levels increase when dosed as a prodrug in liposomal form
HIV/AIDS Drug Development - Broad-spectrum nonnucleoside reverse transcriptase inhibitors have antiviral activity
HIV/AIDS Drug Resistance - Drug-resistance mutations identified in HAART-naive HIV-infected patients
HIV/AIDS Genetics & Genomics - CYP2B6 genetic variability determined for populations of African and Asian origin
HIV/AIDS HAART - Boosted indinavir plus efavirenz yields durable response in patients failing NRTI regimens
HIV/AIDS HAART - HAART efficacy and toxicity widely variable between HIV-infected patients
HIV/AIDS HAART - HAART promotes salivary microbiota in HIV-positive women
HIV/AIDS HAART - Researchers' findings advance HIV/AIDS HAART research
HIV/AIDS Hypercholesterolemia - Risk factors identified for hypercholesterolemia risk at HAART initiation
HIV/AIDS Opportunistic Infection - Withdrawal of PCP prophylaxis after immune reconstitution safe in pediatric HIV/AIDS
HIV/AIDS Pathogenesis - IL-7R alpha loss associated with CD4 T-cell depletion and high IL-7 in HIV/AIDS
HIV/AIDS Pathogenesis - Recent findings in HIV/AIDS pathogenesis provide new insights
HIV/AIDS Prevention - Long-term zidovudine prophylaxis reduces HIV-1 vertical transmission to neonates
HIV/AIDS Preventive Medicine - HIV postexposure prophylaxis for sexually abused children safe and feasible
HIV/AIDS Prognostics - Total lymphocyte count predicts disease progression risk in pediatric HIV/AIDS
HIV/AIDS Therapy - Dextrin sulphate against HIV is well tolerated without systemic absorption
HIV/AIDS Transmission - Clarification is needed of the significance of altered vaginal microflora in HIV-positive women
HIV/AIDS Vertical Transmission - Lower vertical HIV-1 transmission in boys independent of type of delivery or prophylaxis
HIV/AIDS Vertical Transmission - Prevention of mother-to-child HIV transmission integrated into routine antenatal care
Healthcare Costs - Azithromycin may be less costly than levofloxacin in hospitalized pneumonia patients
Infectious Diseases - Avian influenza outbreak in Southeast Asia detailed in report
Infectious Diseases - Pivotal study initiated for antimicrobial central venous catheter
Influenza - Oseltamivir effective against pandemic influenza strains
Influenza Vaccine - Influenza prevention via vaccines and oseltamivir is cost-effective in the Netherlands
Information Technology - Desktop Flu Tracker helps Americans prepare for seasonal flu spread
Medical Devices - First Via Wound Drain product sold by medical device firm
Medical Devices - Maximal barrier precautions tray provides central line insertion safety and infection protection
Mergers & Acquisitions - Antibiotic oritavancin purchased for cash, payments from InterMune
Mycobacterium Tuberculosis - M. tuberculosis PtpB structure reveals diverged fold and buried active site
Nosocomial Infections - Gene cluster coding for antibacterial resistance found in Acinetobacter species
Nosocomial Infections - Microdialysis suitable for assessment of antibiotic levels in lung tissue after heart surgery
Nosocomial Infections - Patient-safety monitoring identifies IV catheter as likely source of infection
Pediatric Cardiology - Report presents five cases of Candida endocarditis in neonates
Personnel - Annarie Lyles named head of business development
Personnel - Robin Toft named to board of company developing tests to detect harmful pathogens
Pharmaceutical Research - MDR-tuberculosis in Iran cured with the use of appropriate treatment regimens
Pharmaceutical Research - Plant-derived vaccines may safeguard against deadly bacterial disease
Pharmaceutical Research - Sampling requirement reduced to determine rifampicin bioequivalence from FDC formulations
Respiratory Medicine - Empiric fluoroquinolone treatment improves response in misdiagnosed pulmonary TB patients
SARS - Antibody against SARS-coronavirus nucleocapsid protein cross-reacts with IL-11
Schistosomiasis - New research in the area of schistosomiasis detailed
Stem Cell Transplantation - Antithymocyte globulin and recipient CMV seronegativity are HUS risk factors after BMT
Tissue Engineering - Incorporation of bFGF-impregnated gelatin microspheres increased wound healing in mouse
Tuberculosis Control - Successful global tuberculosis control strategies evaluated
Tuberculosis Therapy - Point mutations in M. tuberculosis genes linked to drug resistance are identified
Tuberculosis Treatment - Tuberculosis treatment success variable among 18 European countries
Vancomycin - Loss of accessory gene regulator function may explain decreased efficacy of vancomycin
Virology - A viral gene promoter is subject to circadian control
Water-Borne Illness - Home-based water chlorination reduces diarrhea in HIV-infected Ugandans
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