Anti-Infectives Week

Antimicrobials - Epsilon-polylysine has antimicrobial activity against three common pathogens

Drug Resistance - Pair of studies offer new clues to combat antibiotic resistance

Infection Control - Response algorithm controls transmission of airborne-spread diseases

Toxic Shock Syndrome - Prophylactic antibiotics prevent toxic shock syndrome in burn patients

Tuberculosis Therapy - Acquired resistance and eradication of susceptible bacteria can occur concurrently

Adverse Drug Reaction - Antimicrobial agents can cause drug interactions in children treated for cancer

Anti-Infectives - Newer antibiotic more effective against community acquired pneumonia

Antibiotics - Cubicin granted marketing approval in Europe

Antimicrobials - Antimicrobial resistance trends in health care facilities

Avian Influenza - Vaccine provides 100% protection against avian flu virus in animal study

Business & Finance - Drug developer takes final step to eliminate debt by redeeming remaining notes

Business & Finance - Irradiation company receives NASDAQ warning letter

Business & Finance - Peptide company announces strategic milestones for 2006

Business Update - Biotech company restructuring to advance inflammatory arthritis product candidate

Cardiovascular Disease - Neurologic, renal impairment are predictors of mortality in paravalvular abscess patients

Clinical Trials - Noncompliance may underestimate topical microbicide efficacy in clinical trials

Collaborations - Licensing agreement inked with CONRAD for collaboration on microbicide pipeline

Diabetes Complications - Diabetes-enhanced inflammation and apoptosis impact on periodontal pathology is reviewed

Diagnostics - PCR testing enables rapid detection of CSF shunt and ventriculostomy infections

Diagnostics - Real-time PCR rapidly determines rifampin resistant MTB clinical isolates

Disease Associations - Markers predict mortality in HIV-infected patients with end-stage liver disease

Drug Delivery - Nanoparticle drug delivery systems allow sustained antituberculosis drug release

Drug Development - New findings in drug development described

Drug Development - Positive new survival findings reported from phase II, III trials of orBec

Drug Resistance -  Staphylococcus aureus small colony variants are resistant to lactoferricin B

Drug Resistance - Change of antimicrobial use affects resistance in certain Gram-negative bacteria

Drug Resistance - New findings in the area of drug resistance detailed

Drug Resistance - Treatment of multidrug resistant TB led to fluoroquinolone resistance in Taiwan

Drug Safety - Availability and pilot program of Qscan-VAERS announced

Epidemiology - Contemporary international resistant S. pneumoniae clones compared with original isolates

Facilities - Kimberly-Clark joins national initiative to reduce surgical complications

Finance - Medical technology company reports Q4 2005 revenue of $322 million, up 18% over year ago

Genital Warts - Risk of developing genital wart recurrence after 3 months of 5% imiquimod cream use is low

HIV/AIDS Drug Development - Phosphonate prodrugs more active against HIV compared to the parent PMEA

HIV/AIDS Drug Resistance - K103N is the most common mutation in patients receiving antiretroviral therapy in Kampala

HIV/AIDS HAART - DDI has a dose-dependent influence on immune recovery in tenofovir-treated patients

HIV/AIDS HAART - HIV protease mutations predict virological response to lopinavir and ritonavir

HIV/AIDS HAART - Low-dose ritonavir has a modest inhibitory effect on CYP2D6 in extensive metabolizers