Published in Anti-Infectives Week, February 20th, 2006
According to recent research from Turkey, "Real-time PCR was used to determine rifampin resistance in clinical isolates of Mycobacterium tuberculosis. Ninety-six rifampin-resistant isolates and 23 rifampin-susceptible isolates were included in the study."
"A 305-bp region covering the 81-bp 'rifampin resistance-determining region' of rpoB was amplified. Two hybridization probe pairs that covered the most frequent mutation sites in rpoB, codon regions 526 to 531 and 513 to 516, were used.
"The results obtained by...
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